Literature DB >> 4065338

Tenacious binding of lipids to vimentin during its isolation and purification from Ehrlich ascites tumor cells.

P Traub, G Perides, A Scherbarth, U Traub.   

Abstract

Vimentin enriched in cytoskeletal frameworks by Triton X-100 extraction of Ehrlich ascites tumor cells and purified from a low ionic strength extract of the cell residues by (NH4)2SO4 precipitation and DEAE-Sepharose and ssDNA-cellulose chromatography in the presence of 6 M urea was highly contaminated with lipids. Thin-layer chromatography of a chloroform-methanol extract of the purified protein revealed, besides small amounts of phospholipids, the presence of large quantities of neutral lipids.

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Year:  1985        PMID： 4065338     DOI： 10.1016/0014-5793(85)80155-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  7 in total

1.  An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells.

Authors:  Kathryn P Trogden; Rachel A Battaglia; Parijat Kabiraj; Victoria J Madden; Harald Herrmann; Natasha T Snider
Journal:  FASEB J       Date:  2018-01-18       Impact factor: 5.191

Review 2.  Interaction of the cytoskeleton with the plasma membrane.

Authors:  V Niggli; M M Burger
Journal:  J Membr Biol       Date:  1987       Impact factor: 1.843

3.  Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.

Authors:  Amanda Kirane; Jason E Toombs; Katherine Ostapoff; Juliet G Carbon; Sara Zaknoen; Jordan Braunfeld; Roderich E Schwarz; Francis J Burrows; Rolf A Brekken
Journal:  Clin Cancer Res       Date:  2012-07-24       Impact factor: 12.531

4.  Tumour epithelial vimentin expression and outcome of pancreatic ductal adenocarcinomas.

Authors:  A Handra-Luca; S-M Hong; K Walter; C Wolfgang; R Hruban; M Goggins
Journal:  Br J Cancer       Date:  2011-03-29       Impact factor: 7.640

5.  Alterations in lipid metabolism gene expression and abnormal lipid accumulation in fibroblast explants from giant axonal neuropathy patients.

Authors:  Conrad L Leung; Yinghua Pang; Chang Shu; Dmitry Goryunov; Ronald K H Liem
Journal:  BMC Genet       Date:  2007-03-01       Impact factor: 2.797

6.  A Defective Crosstalk Between Neurons and Müller Glial Cells in the rd1 Retina Impairs the Regenerative Potential of Glial Stem Cells.

Authors:  Yanel A Volonté; Harmonie Vallese-Maurizi; Marcos J Dibo; Victoria B Ayala-Peña; Andrés Garelli; Samanta R Zanetti; Axel Turpaud; Cheryl Mae Craft; Nora P Rotstein; Luis E Politi; Olga L German
Journal:  Front Cell Neurosci       Date:  2019-07-25       Impact factor: 5.505

7.  microRNA-21 Regulates Stemness in Pancreatic Ductal Adenocarcinoma Cells.

Authors:  Maria Mortoglou; Francesc Miralles; Elif Damla Arisan; Alwyn Dart; Stipo Jurcevic; Sigrun Lange; Pinar Uysal-Onganer
Journal:  Int J Mol Sci       Date:  2022-01-24       Impact factor: 5.923
  7 in total

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