Literature DB >> 4065305

Quantitative cytophotometric analyses of mesenteric mast cell granulation in acute soman intoxicated rats.

J A Doebler, T M Shih, A Anthony.   

Abstract

Effects of the organophosphate neurotoxin soman on rat mesenteric mast cell granule content were determined using scanning-integrating microdensitometric analysis of individual cell metachromasia. Mast cell degranulation was evidenced both with sublethal (0.5 LD50) and lethal (1.5 LD50) dosages and as early as 3-10 min post-injection. These data indicate a possible contribution of mast cell autacoids in the genesis of organophosphate-induced respiratory and circulatory collapse.

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Year:  1985        PMID： 4065305     DOI： 10.1007/BF01950034

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  Interconversion of cholinesterase enzyme activity units by the manual delta pH method and a recommended automated method.

Authors:  W A Groff; A Kaminskis; R I Ellin
Journal:  Clin Toxicol       Date:  1976       Impact factor: 4.467

2.  A quantitative spectrophotometric study of the mast cell.

Authors:  J W KELLY; G BLOOM
Journal:  Exp Cell Res       Date:  1959-03       Impact factor: 3.905

3.  A method for in situ cytophotometric estimation of absolute amount of ribonucleic acid using azure B1.

Authors:  J R Shea
Journal:  J Histochem Cytochem       Date:  1970-02       Impact factor: 2.479

4.  The effects of organophosphate-induced cholinergic stimulation on the antibody response to sheep erythrocytes in inbred mice.

Authors:  G P Casale; S D Cohen; R A DiCapua
Journal:  Toxicol Appl Pharmacol       Date:  1983-04       Impact factor: 4.219

5.  A sequence of biochemical events in the antigen-induced release of chemical mediators from sensitized human lung tissue.

Authors:  M Kaliner; K F Austen
Journal:  J Exp Med       Date:  1973-11-01       Impact factor: 14.307

6.  Immunological release of histamine and slow reacting substance of anaphylaxis from human lung.

Authors:  M Kaliner; R P Orange; K F Austen
Journal:  J Exp Med       Date:  1972-09-01       Impact factor: 14.307
  6 in total
  2 in total

Review 1.  A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation.

Authors:  Christopher N Banks; Pamela J Lein
Journal:  Neurotoxicology       Date:  2012-02-10       Impact factor: 4.294

2.  Protective effects of the antihistamine promethazine aginst acute paraxon-methyl and dicrotophos toxicity in adult rats.

Authors:  Syed M Nurulain; Shreesh Ojha; Mohammad Shafiullah; Nadia Khan; Murat Oz; Bassem Sadek
Journal:  Int J Clin Exp Med       Date:  2015-10-15
  2 in total

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