| Literature DB >> 4064567 |
P J Drew, J P Monson, H K Metcalfe, S J Evans, R A Iles, R D Cohen.
Abstract
The effect of arginine vasopressin (AVP) on ureagenesis was measured in isolated rat hepatocytes with ammonium chloride and L(+)-lactate as substrates. AVP was found to stimulate urea synthesis and the dose-response curve suggests that such an effect is present at concentrations of the hormone as low as 25-50 pmol/l. Both the dose-response curve and the concentrations of NH+4 employed suggest that the effect observed could be of physiological significance.Entities:
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Year: 1985 PMID: 4064567 DOI: 10.1042/cs0690231
Source DB: PubMed Journal: Clin Sci (Lond) ISSN: 0143-5221 Impact factor: 6.124