Literature DB >> 4063193

Pyoderma gangrenosum treated with cyclosporin A.

R K Curley, A W Macfarlane, C F Vickers.   

Abstract

A 49-year-old woman with a 14-year history of pyoderma gangrenosum unresponsive to a variety of systemic and topical treatments was given oral cyclosporin A (CyA), a potent immunosuppressive agent widely used in organ transplantation for the prophylaxis of acute graft-versus-host disease. Improvement and subsequent healing of the lesions was evident within 3 weeks of starting treatment and has continued for the duration of treatment (12 months).

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Year:  1985        PMID: 4063193     DOI: 10.1111/j.1365-2133.1985.tb02385.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  10 in total

Review 1.  Dermatology.

Authors:  M H Rustin
Journal:  Postgrad Med J       Date:  1990-11       Impact factor: 2.401

2.  Infliximab for the treatment of pyoderma gangrenosum: a randomised, double blind, placebo controlled trial.

Authors:  T N Brooklyn; M G S Dunnill; A Shetty; J J Bowden; J D L Williams; C E M Griffiths; A Forbes; R Greenwood; C S Probert
Journal:  Gut       Date:  2005-09-27       Impact factor: 23.059

3.  Topical cyclosporin A in nickel contact hypersensitivity: results of a preliminary clinical and immunohistochemical investigation.

Authors:  R D Aldridge; H F Sewell; G King; A W Thomson
Journal:  Clin Exp Immunol       Date:  1986-12       Impact factor: 4.330

Review 4.  Important cutaneous manifestations of inflammatory bowel disease.

Authors:  L B Trost; J K McDonnell
Journal:  Postgrad Med J       Date:  2005-09       Impact factor: 2.401

5.  Pyoderma gangrenosum: From historical perspectives to emerging investigations.

Authors:  Misty M Hobbs; Alex G Ortega-Loayza
Journal:  Int Wound J       Date:  2020-05-06       Impact factor: 3.315

Review 6.  Neutrophilic dermatoses: pyoderma gangrenosum and Sweet's syndrome.

Authors:  J T Lear; M T Atherton; J P Byrne
Journal:  Postgrad Med J       Date:  1997-02       Impact factor: 2.401

7.  Suppression of local and systemic responses in streptococcal cell wall-induced acute inflammation of the air pouch by cyclosporine A. Comparison with the effects of two anti-inflammatory bis-benzimidazoles.

Authors:  J Dieter Geratz; K B Pryzwansky; J H Schwab; S K Anderle; R R Tidwell
Journal:  Am J Pathol       Date:  1993-04       Impact factor: 4.307

8.  Cyclosporin-responsive hidradenitis suppurativa.

Authors:  D A Buckley; S Rogers
Journal:  J R Soc Med       Date:  1995-05       Impact factor: 5.344

9.  Skin manifestations of inflammatory bowel disease.

Authors:  Brian L Huang; Stephanie Chandra; David Quan Shih
Journal:  Front Physiol       Date:  2012-02-06       Impact factor: 4.566

10.  Pyoderma gangrenosum.

Authors:  R K Curley
Journal:  J R Soc Med       Date:  1991-06       Impact factor: 18.000

  10 in total

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