Literature DB >> 4062875

Evidence for adrenergic control of transcellular calcium distribution in liver.

C E Hill, A P Dawson, J S Pryor.   

Abstract

Free Ca2+ concentration and 45Ca flux were measured in the perfusate and bile of the perfused rat liver. With a perfusate Ca2+ concentration of 1 mM, the bile concentration was 0.35 mM. The ratio of 45Ca in bile to that in blood increased from 0.3 to 0.6 over 90 min of perfusion. Both verapamil and adrenaline (via alpha-adrenergic receptors) increased the 45Ca bile/perfusate ratio to 0.8. Adrenaline infusion increased the bile Ca2+ concentration to 0.8 mM. This decreased to 0.35 mM after the infusion was stopped.

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Year:  1985        PMID: 4062875      PMCID: PMC1152677          DOI: 10.1042/bj2300733

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  21 in total

1.  The relationship between taurocholate secretion rate and bile production in the unanesthetized dog during cholinergic blockade and during secretin administration.

Authors:  R PREISIG; H L COOPER; H O WHEELER
Journal:  J Clin Invest       Date:  1962-05       Impact factor: 14.808

2.  Calcium movements in in situ mitochondria following activation of alpha-adrenergic receptors in rat liver cells.

Authors:  J Poggioli; B Berthon; M Claret
Journal:  FEBS Lett       Date:  1980-06-30       Impact factor: 4.124

3.  Fluxes and distribution of calcium in rat liver cells: kinetic analysis and identification of pools.

Authors:  B Claret-Berthon; M Claret; J L Mazet
Journal:  J Physiol       Date:  1977-11       Impact factor: 5.182

4.  alpha-Adrenergic activation of phosphorylase in liver cells involves mobilization of intracellular calcium without influx of extracellular calcium.

Authors:  P F Blackmore; B P Hughes; E A Shuman; J H Exton
Journal:  J Biol Chem       Date:  1982-01-10       Impact factor: 5.157

5.  alpha-Adrenergic blockade and inhibition of A23187 mediated Ca2+ uptake by the calcium antagonist verapamil in rat liver cells.

Authors:  P F Blackmore; M F El-Refai; J H Exton
Journal:  Mol Pharmacol       Date:  1979-05       Impact factor: 4.436

6.  Role of calcium in the hormonal regulation of liver metabolism.

Authors:  J R Williamson; R H Cooper; J B Hoek
Journal:  Biochim Biophys Acta       Date:  1981-12-30

7.  Hormonal effects on calcium homeostasis in isolated hepatocytes.

Authors:  E Murphy; K Coll; T L Rich; J R Williamson
Journal:  J Biol Chem       Date:  1980-07-25       Impact factor: 5.157

8.  Inhibitory effect on calcium channel blockers on alpha -adrenergic activation of glycogenolysis and calcium efflux in perfused rat liver.

Authors:  S Kimura; Y Koide; R Tada; K Abe; E Ogata
Journal:  Endocrinol Jpn       Date:  1981-02

9.  A kinetic analysis of the effects of adrenaline on calcium distribution in isolated rat liver parenchymal cells.

Authors:  G J Barritt; J C Parker; J C Wadsworth
Journal:  J Physiol       Date:  1981-03       Impact factor: 5.182

10.  Gluconeogenesis in the perfused rat liver.

Authors:  R Hems; B D Ross; M N Berry; H A Krebs
Journal:  Biochem J       Date:  1966-11       Impact factor: 3.857

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  3 in total

1.  Acute effects of cholestatic and choleretic bile salts on vasopressin- and glucagon-induced hepato-biliary calcium fluxes in the perfused rat liver.

Authors:  Y Hamada; A Karjalainen; B A Setchell; J E Millard; F L Bygrave
Journal:  Biochem J       Date:  1992-04-15       Impact factor: 3.857

2.  The synergistic action (cross-talk) of glucagon and vasopressin induces early bile flow and plasma-membrane calcium fluxes in the perfused rat liver.

Authors:  A Karjalainen; F L Bygrave
Journal:  Biochem J       Date:  1994-07-01       Impact factor: 3.857

3.  Concomitant stimulation by vasopressin of biliary and perfusate calcium fluxes in the perfused rat liver.

Authors:  Y Hamada; A Karjalainen; B A Setchell; J E Millard; F L Bygrave
Journal:  Biochem J       Date:  1992-01-15       Impact factor: 3.857

  3 in total

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