| Literature DB >> 4060182 |
P Simon, H Ottenwälder, H M Bolt.
Abstract
The question of carcinogenicity of vinyl acetate led us to perform a DNA binding assay in vivo in rats, using 14C-labelled vinyl acetate. After administration of [14C]vinyl acetate to male and female Fischer-344 rats, either orally or by inhalation, no specific hepatic DNA adducts, known to occur after administration of labelled vinyl halides or vinyl carbamates, could be detected in hepatic tissues.Entities:
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Year: 1985 PMID： 4060182 DOI： 10.1016/0378-4274(85)90128-6
Source DB: PubMed Journal: Toxicol Lett ISSN： 0378-4274 Impact factor: 4.372