Literature DB >> 4058450

Methods for study of mutations and mutagenesis in human lymphocytes.

A A Morley, K J Trainor, J L Dempsey, R S Seshadri.   

Abstract

Detailed methods are presented for measurement and study of in vivo mutations and in vitro mutagenesis in human lymphocytes. The methods described include preparation of conditioned medium containing interleukin-2, enumeration of mutant clones, in vitro mutagenesis, and expansion of mutant clones for further study.

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Year:  1985        PMID: 4058450     DOI: 10.1016/0165-1161(85)90005-6

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  5 in total

1.  Mutation rates at the glycophorin A and HPRT loci in uranium miners exposed to radon progeny.

Authors:  E M Shanahan; D Peterson; D Roxby; J Quintana; A A Morely; A Woodward
Journal:  Occup Environ Med       Date:  1996-07       Impact factor: 4.402

2.  Mutations in human lymphocytes commonly involve gene duplication and resemble those seen in cancer cels.

Authors:  D R Turner; S A Grist; M Janatipour; A A Morley
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

3.  Mutagenic activity of BKV and JCV in human and other mammalian cells.

Authors:  M Theile; G Grabowski
Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

4.  Mutagenesis after cancer therapy.

Authors:  K T Kelsey; M Caggana; P M Mauch; C N Coleman; J R Clark; H L Liber
Journal:  Environ Health Perspect       Date:  1993-10       Impact factor: 9.031

5.  Modulation of antifolate cytotoxicity by metabolites from dying cells in a lymphocyte clonal assay.

Authors:  J M Hughes; A deFazio; M H Tattersall
Journal:  Br J Cancer       Date:  1988-05       Impact factor: 7.640

  5 in total

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