Literature DB >> 405778

In vitro anti-mycobacterial activity of some new amino-glycoside antibiotics.

P R Gangadharam, E R Candler.   

Abstract

Four new aminoglycoside antibiotics, namely gentamycin, amikacin, tobramycin and sisiomycin were tested against several pathogenic strains of so-called 'typical' and 'atypical' mycobacteria. Only amikacin exhibited considerable in vitro anti-mycobacterial activity against Mycobacterium tuberculosis and not against other mycobacterial pathogens. None of the other three antibiotics exhibited activity against any of the mycobacteria at low concentrations.

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Year:  1977        PMID: 405778     DOI: 10.1016/s0041-3879(77)80008-1

Source DB:  PubMed          Journal:  Tubercle        ISSN: 0041-3879


  4 in total

Review 1.  Use of aminoglycosides in treatment of infections due to intracellular bacteria.

Authors:  M Maurin; D Raoult
Journal:  Antimicrob Agents Chemother       Date:  2001-11       Impact factor: 5.191

2.  Bacteriostatic and bactericidal activities of gentamicin alone and in combination with clarithromycin against Mycobacterium avium.

Authors:  L B Heifets; P J Lindholm-Levy; R D Comstock
Journal:  Antimicrob Agents Chemother       Date:  1992-08       Impact factor: 5.191

3.  Liposome-encapsulated-gentamicin therapy of Mycobacterium avium complex infection in beige mice.

Authors:  S P Klemens; M H Cynamon; C E Swenson; R S Ginsberg
Journal:  Antimicrob Agents Chemother       Date:  1990-06       Impact factor: 5.191

4.  Susceptibility of streptomycin-resistant Mycobacterium tuberculosis strains to amikacin.

Authors:  S E Hoffner; G Källenius
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1988-04       Impact factor: 3.267

  4 in total

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