Literature DB >> 4054629

Structure of the chromosomal gene for human serum prealbumin.

H Sasaki, N Yoshioka, Y Takagi, Y Sakaki.   

Abstract

The human prealbumin gene has been cloned and its complete nucleotide sequence determined. The gene has a size of about 6.9 kb and is composed of four exons and three introns. Two Alu family sequences having opposing polarity were found in introns. In the 5'-flanking region, we found two overlapping sequences which have extensive homology to the glucocorticoid-responsive element. Three sequences identical with the enhancer core sequence were identified in introns and the 3'-flanking region. Unusual tandem repeats of a sequence, TTTTG, were also found in the 5'-flanking region and introns.

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Year:  1985        PMID： 4054629     DOI： 10.1016/0378-1119(85)90272-0

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  29 in total

1.  Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt).

Authors:  Jacquelyn L Sikora; Mark W Logue; Gloria G Chan; Brian H Spencer; Tatiana B Prokaeva; Clinton T Baldwin; David C Seldin; Lawreen H Connors
Journal:  Hum Genet       Date:  2014-11-04       Impact factor: 4.132

2.  Stress and glucocorticoids increase transthyretin expression in rat choroid plexus via mineralocorticoid and glucocorticoid receptors.

Authors:  A Martinho; I Gonçalves; M Costa; C R Santos
Journal:  J Mol Neurosci       Date:  2012-02-28       Impact factor: 3.444

3.  A new isoleucine substitution of Val-20 in transthyretin tetramers selectively impairs dimer-dimer contacts and causes systemic amyloidosis.

Authors:  D E Jenne; K Denzel; P Blätzinger; P Winter; B Obermaier; R P Linke; K Altland
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

4.  An association study between the transthyretin (TTR) gene and mental retardation.

Authors:  Jun Li; Jian-Jun Gao; Fu-Chang Zhang; Qing-He Xing; Fang-Li Dang; Xiao-Cai Gao; Shi-Wei Duan; Zi-Jian Zheng; Xue-Qing Qian; Wei Qin; Xing-Wang Li; Yan-Feng Han; Jing Li; Guo-Yin Feng; D St Clair; Lin He
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2005-12-19       Impact factor: 5.270

5.  Prenatal diagnosis of familial amyloidotic polyneuropathy: evidence for an early expression of the associated transthyretin methionine 30.

Authors:  M R Almeida; I L Alves; Y Sakaki; P P Costa; M J Saraiva
Journal:  Hum Genet       Date:  1990-10       Impact factor: 4.132

6.  From molecular variant to disease: initial steps in evaluating the association of transthyretin M119 with disease.

Authors:  S Ii; J L Sobell; S S Sommer
Journal:  Am J Hum Genet       Date:  1992-01       Impact factor: 11.025

7.  Homozygosity for the met30 transthyretin gene in a Turkish kindred with familial amyloidotic polyneuropathy.

Authors:  J Skare; H Yazici; E Erken; H Dede; A Cohen; A Milunsky; M Skinner
Journal:  Hum Genet       Date:  1990-11       Impact factor: 4.132

8.  A DNA test for Indiana/Swiss hereditary amyloidosis (FAP II).

Authors:  M R Wallace; P M Conneally; M D Benson
Journal:  Am J Hum Genet       Date:  1988-08       Impact factor: 11.025

9.  Assignment of the prealbumin (PALB) gene (familial amyloidotic polyneuropathy) to human chromosome region 18q11.2-q12.1.

Authors:  R S Sparkes; H Sasaki; T Mohandas; K Yoshioka; I Klisak; Y Sakaki; C Heinzmann; M I Simon
Journal:  Hum Genet       Date:  1987-02       Impact factor: 4.132

10.  A homozygous transthyretin variant associated with senile systemic amyloidosis: evidence for a late-onset disease of genetic etiology.

Authors:  D R Jacobson; P D Gorevic; J N Buxbaum
Journal:  Am J Hum Genet       Date:  1990-07       Impact factor: 11.025
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