Literature DB >> 4052435

The primary structure of mitochondrial aspartate aminotransferase from human heart.

F Martini, S Angelaccio, D Barra, S Pascarella, B Maras, S Doonan, F Bossa.   

Abstract

The complete amino acid sequence of the mitochondrial aspartate aminotransferase (L-aspartate:2-oxoglutarate aminotransferase, EC 2.6.1.1) from human heart has been determined based mainly on analysis of peptides obtained by digestion with trypsin and by chemical cleavage with cyanogen bromide. Comparison of the sequence with those of the isotopic isoenzymes from pig, rat and chicken showed 27, 29 and 55 differences, respectively, out of a total of 401 amino acid residues. Evidence for structural microheterogeneity at position 317 has also been obtained.

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Year:  1985        PMID： 4052435     DOI： 10.1016/0167-4838(85)90172-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  5 in total

Review 1.  A comparison of pyridoxal 5'-phosphate dependent decarboxylase and transaminase enzymes at a molecular level.

Authors:  D M Smith; N R Thomas; D Gani
Journal:  Experientia       Date:  1991-12-01

Review 2.  Structure, expression, and function of kynurenine aminotransferases in human and rodent brains.

Authors:  Qian Han; Tao Cai; Danilo A Tagle; Jianyong Li
Journal:  Cell Mol Life Sci       Date:  2009-10-15       Impact factor: 9.261

3.  The amino acid sequence of cytosolic aspartate aminotransferase from human liver.

Authors:  J M Doyle; M E Schininà; F Bossa; S Doonan
Journal:  Biochem J       Date:  1990-09-15       Impact factor: 3.857

4.  Rapid purification and thermostability of the cytoplasmic aspartate aminotransferase from carrot suspension cultures.

Authors:  F J Turano; B J Wilson; B F Matthews
Journal:  Plant Physiol       Date:  1991-10       Impact factor: 8.340

5.  The complete amino acid sequences of cytosolic and mitochondrial aspartate aminotransferases from horse heart, and inferences on evolution of the isoenzymes.

Authors:  S Doonan; F Martini; S Angelaccio; S Pascarella; D Barra; F Bossa
Journal:  J Mol Evol       Date:  1986       Impact factor: 2.395
  5 in total

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