Literature DB >> 4051533

Leukonychia punctata and pitted nails in alopecia areata.

W I Dotz, C D Lieber, P J Vogt.   

Abstract

A 36-year-old man with long-standing alopecia areata was noted to have both leukonychia punctata and pitted nails. Histopathologic evaluation of the leukonychia punctata revealed multiple discrete parakeratotic foci throughout the entire thickness of the nail plate, suggesting both proximal and distal matrix involvement. The finding of shallow pits lined with residual adherent parakeratotic cells suggests that the pathogenesis of nail pits in alopecia areata is similar to that of psoriasis; a result of shedding of parakeratotic cell aggregates from the nail plate.

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Year:  1985        PMID: 4051533

Source DB:  PubMed          Journal:  Arch Dermatol        ISSN: 0003-987X


  3 in total

Review 1.  Alopecia Areata: a Comprehensive Review of Pathogenesis and Management.

Authors:  Ralph M Trüeb; Maria Fernanda Reis Gavazzoni Dias
Journal:  Clin Rev Allergy Immunol       Date:  2018-02       Impact factor: 8.667

2.  Severe onycholysis in a card illusionist with alopecia areata universalis.

Authors:  Antonella Tosti; Massimiliano Pazzaglia; Michela Venturi; Nilton Chiacchio Chiacchio
Journal:  Int J Trichology       Date:  2013-04

Review 3.  Leukonychia: What Can White Nails Tell Us?

Authors:  Matilde Iorizzo; Michela Starace; Marcel C Pasch
Journal:  Am J Clin Dermatol       Date:  2022-02-02       Impact factor: 7.403

  3 in total

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