Literature DB >> 4050481

Early effects of denervation on isometric and isotonic contractile properties of rat skeletal muscles.

K Gundersen.   

Abstract

The contractile properties of the fast-twitch m. extensor digitorum longus (EDL) and the slow-twitch m. soleus were examined after 5 days of denervation. An increase in twitch time to peak, twitch half relaxation time and twitch/tetanus ratio was observed. The EDL also showed a moderate decrease in maximal isotonic shortening velocity, which is taken as an indication that the contractile proteins are affected. A fatigue test showed that the EDL became less fatigable and the soleus less fatigue resistant after denervation.

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Year:  1985        PMID： 4050481     DOI： 10.1111/j.1748-1716.1985.tb00047.x

Source DB:  PubMed          Journal:  Acta Physiol Scand        ISSN： 0001-6772


  9 in total

Review 1.  The denervated muscle: facts and hypotheses. A historical review.

Authors:  Menotti Midrio
Journal:  Eur J Appl Physiol       Date:  2006-08-03       Impact factor: 3.078

Review 2.  Excitation-transcription coupling in skeletal muscle: the molecular pathways of exercise.

Authors:  Kristian Gundersen
Journal:  Biol Rev Camb Philos Soc       Date:  2010-10-06

3.  Electrical stimulation of transplanted motoneurons improves motor unit formation.

Authors:  Yang Liu; Robert M Grumbles; Christine K Thomas
Journal:  J Neurophysiol       Date:  2014-05-21       Impact factor: 2.714

4.  Electrical stimulation resembling normal motor-unit activity: effects on denervated fast and slow rat muscles.

Authors:  T Eken; K Gundersen
Journal:  J Physiol       Date:  1988-08       Impact factor: 5.182

Review 5.  The ups and downs of gene regulation by electrical activity in skeletal muscles.

Authors:  Zaheer A Rana; Kristian Gundersen; Andres Buonanno
Journal:  J Muscle Res Cell Motil       Date:  2010-02-05       Impact factor: 2.698

6.  Id-1 as a possible transcriptional mediator of muscle disuse atrophy.

Authors:  K Gundersen; J P Merlie
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-26       Impact factor: 11.205

7.  Nerve-dependent changes in skeletal muscle myosin heavy chain after experimental denervation and cross-reinnervation and in a demyelinating mouse model of Charcot-Marie-Tooth disease type 1A.

Authors:  Alison M Maggs; Clare Huxley; Simon M Hughes
Journal:  Muscle Nerve       Date:  2008-12       Impact factor: 3.217

Review 8.  Neuromuscular adaptations to respiratory muscle inactivity.

Authors:  Carlos B Mantilla; Gary C Sieck
Journal:  Respir Physiol Neurobiol       Date:  2009-09-08       Impact factor: 1.931

9.  Paralysis of rat skeletal muscle equally affects contractile properties as does permanent denervation.

Authors:  M Buffelli; E Pasino; A Cangiano
Journal:  J Muscle Res Cell Motil       Date:  1997-12       Impact factor: 3.352
  9 in total

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