Literature DB >> 4049805

Thirty-five-day modified red cells and 7-day stored platelet concentrates from triple bags of identical PVC formulation.

V A Lovric, G T Archer, L Wisdom, J Robson, J Raftos, N Coulits, A Ribeiro, M Stewart, J Jindra, M Schuller.   

Abstract

There is continuous need for blood components with long shelf life. To this end the 'circle' triple pack has been modified to provide 35-day red cell and 7-day platelet concentrates, in PVC bags of identical formulation and 0.4 mm thick. The plasticizer is a mixture of DEHP and TOTM (CLX Mark II). The primary pack contains 63 ml of CP 277.5 mM glucose. The third pack contains 100 ml of citric acid 2 mM, trisodium citrate 20 mM, NaH2PO4 20 mM, NaCl 123 mM, glucose 40 mM, and adenine 1.26 mM. Plasma is adenine-free. With these modifications both hard- and soft-spun red cells gave satisfactory biochemical and autologous survival indices up to 35 days of storage, the haematocrit not exceeding 60%. Platelet concentrates were acceptable at 7 days of shelf-life.

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Year:  1985        PMID: 4049805     DOI: 10.1111/j.1423-0410.1985.tb00791.x

Source DB:  PubMed          Journal:  Vox Sang        ISSN: 0042-9007            Impact factor:   2.144


  3 in total

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  3 in total

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