Literature DB >> 404575

Degradation of hypothalamic hormones.

K Bauer.   

Abstract

The enzymatic fragmentation of TRH (pyroGlu-His-Pro-NH2) by serum, hypothalamic and hypophyseal tissue was investigated. As primary cleavage product only His-Pro-NH2 was detected when TRH was incubated with serum while with the tissue preparations the formation of His-Pro-NH2, deamido-TRH and prolineamide could be detected as enzymatically formed primary fragments.

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Year:  1977        PMID: 404575     DOI: 10.1007/bf00587778

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN: 0028-1298            Impact factor:   3.000


  3 in total

1.  Regulation of degradation of thyrotropin releasing hormone by thyroid hormones.

Authors:  K Bauer
Journal:  Nature       Date:  1976-02-19       Impact factor: 49.962

2.  Attempts toward biosynthesis of the thyrotropin-releasing hormone and studies on its breakdown in hypothalamic tissue preparations.

Authors:  K Bauer; F Lipmann
Journal:  Endocrinology       Date:  1976-07       Impact factor: 4.736

3.  Characteristics of the plasma TRH-degrading enzyme.

Authors:  K M Knigge; D Schock
Journal:  Neuroendocrinology       Date:  1975       Impact factor: 4.914

  3 in total

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