Literature DB >> 4045548

Subcellular distribution of calcium- and calmodulin-dependent myosin light chain phosphorylating activity in rat cerebral cortex.

A M Edelman, D D Hunter, A E Hendrickson, E G Krebs.   

Abstract

The subcellular distribution of Ca2+- and calmodulin-dependent myosin light chain phosphorylating activity in rat cerebral cortex was studied. The activity showed a high degree of association to nerve endings (either crude or purified by discontinuous sucrose density gradient centrifugation). After osmotic shock of the nerve endings, the activity was largely membrane associated and could not be released from membranes by freeze-thawing, dilution, 75 mM NaCl or 4 mM EDTA. The association of Ca2+/calmodulin-dependent myosin light chain phosphorylating activity with synaptosomal membranes suggests a role for calcium-dependent myosin phosphorylation in events relating to neurotransmission.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 4045548      PMCID： PMC6565136     

Source DB:  PubMed          Journal:  J Neurosci        ISSN： 0270-6474            Impact factor:   6.167


  8 in total

1.  Na/K-ATPase under oxidative stress: molecular mechanisms of injury.

Authors:  D Dobrota; M Matejovicova; E G Kurella; A A Boldyrev
Journal:  Cell Mol Neurobiol       Date:  1999-02       Impact factor: 5.046

2.  Identification, kinetic properties and intracellular localization of the (Ca(2+)-Mg2+)-ATPase from the intracellular stores of chicken cerebellum.

Authors:  F Michelangeli; F Di Virgilio; A Villa; P Podini; J Meldolesi; T Pozzan
Journal:  Biochem J       Date:  1991-05-01       Impact factor: 3.857

3.  Ischemia-induced inhibition of active calcium transport into gerbil brain microsomes: effect of anesthetics and models of ischemia.

Authors:  P Racay; P Kaplán; J Lehotský
Journal:  Neurochem Res       Date:  2000-02       Impact factor: 3.996

4.  Iron-induced inhibition of Na+, K(+)-ATPase and Na+/Ca2+ exchanger in synaptosomes: protection by the pyridoindole stobadine.

Authors:  P Kaplán; M Matejovicová; V Mézesová
Journal:  Neurochem Res       Date:  1997-12       Impact factor: 3.996

5.  Change in fluidity of brain endoplasmic reticulum membranes by oxygen free radicals: a protective effect of stobadine, alpha-tocopherol acetate, and butylated hydroxytoluene.

Authors:  P Kaplán; P Racay; J Lehotský; V Mézesová
Journal:  Neurochem Res       Date:  1995-07       Impact factor: 3.996

6.  A cellular mechanism for dendritic spine loss in the pilocarpine model of status epilepticus.

Authors:  Jonathan E Kurz; Bryan J Moore; Scott C Henderson; John N Campbell; Severn B Churn
Journal:  Epilepsia       Date:  2008-05-08       Impact factor: 5.864

7.  Dual regulation of Ca2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx.

Authors:  R P Xiao; H Cheng; W J Lederer; T Suzuki; E G Lakatta
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-27       Impact factor: 11.205

8.  Heterogeneity of microsomal Ca2+ stores in chicken Purkinje neurons.

Authors:  P Volpe; A Villa; E Damiani; A H Sharp; P Podini; S H Snyder; J Meldolesi
Journal:  EMBO J       Date:  1991-11       Impact factor: 11.598
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.