| Literature DB >> 4045194 |
C S Song, J H Yu, D H Bai, P Y Hester, K H Kim.
Abstract
Simple methods for the generation, purification, and assay of antibodies to the alpha-subunit of insulin receptor from eggs of immunized hens have been described. Chicken antibodies against the alpha-subunit inhibit insulin binding to the receptor and stimulate glucose oxidation as well as autophosphorylation of the beta-subunit. Thus the properties of chicken antibodies are very similar to those of antibodies found in human autoimmune diseases and different from rabbit antibodies obtained against the same antigen.Entities:
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Year: 1985 PMID: 4045194
Source DB: PubMed Journal: J Immunol ISSN: 0022-1767 Impact factor: 5.422