Literature DB >> 404479

Changes in hemodynamic parameters, inotropic state, and myocardial oxygen consumption owing to intravenous application of nitroglycerin.

G Hempelmann, S Piepenbrock, W Seitz, G Karliczek.   

Abstract

Changes in hemodynamics, inotropic state, and myocardial oxygen consumptom were investigated in a total of 70 patients with coronary disease after intravenous application of nitroglycerin (0.4 mg., 0.2 mg., and 2 mg. per hour). The results demonstrate that nitroglycerin enlarges therapeutic possibilities during and immediately after operations in patients with limited coronary reserve. The decrease in myocardial oxygen consumption, dependent on dose, ranged between 15.8 and 22.9 per cent.

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Year:  1977        PMID： 404479

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN： 0022-5223            Impact factor:   5.209


  4 in total

Review 1.  Intravenous glyceryl trinitrate (nitroglycerin). A review of its pharmacological properties and therapeutic efficacy.

Authors:  E M Sorkin; R N Brogden; J A Romankiewicz
Journal:  Drugs       Date:  1984-01       Impact factor: 9.546

2.  Automated infusion of nitroglycerin to control arterial hypertension during cardiac surgery.

Authors:  S A Hoeksel; J J Schreuder; J A Blom; J G Maessen; O C Penn
Journal:  Intensive Care Med       Date:  1996-07       Impact factor: 17.440

3.  Myocardial and systemic effects of nitroglycerin, given awake and during anaesthesia in coronary patients.

Authors:  E A Moffitt; D H Sethna; R J Gray; M J Raymond; J A Bussell; J M Matloff
Journal:  Can Anaesth Soc J       Date:  1983-07

4.  Hemodynamic effects of SIN-1 in acute left heart failure.

Authors:  T M Ibrahim; P H Unger; J Sobolski; P Depelchin; M Jottrand; S Degre
Journal:  Cardiovasc Drugs Ther       Date:  1989-08       Impact factor: 3.727
  4 in total

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