Literature DB >> 4043315

Calcium accelerates cholesterol phase transitions in analog bile.

M M Berenson, J R Cardinal.   

Abstract

Analog bile supersaturated with cholesterol was constituted, filtered and divided into equal portions containing no calcium or calcium, 2.5-15 mM. Aliquots were removed over the next 48 h and filtrates analyzed for cholesterol, bile acid and lecithin. Calcium accelerated cholesterol loss from solution in a dose-related fashion.

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Year:  1985        PMID： 4043315     DOI： 10.1007/bf01952079

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  Interactions between ionized calcium and sodium taurocholate: bile salts are important buffers for prevention of calcium-containing gallstones.

Authors:  E W Moore; L Celic; J D Ostrow
Journal:  Gastroenterology       Date:  1982-11       Impact factor: 22.682

2.  Inhibition of cholesterol crystal formation by apolipoproteins in supersaturated model bile.

Authors:  A Kibe; R T Holzbach; N F LaRusso; S J Mao
Journal:  Science       Date:  1984-08-03       Impact factor: 47.728

3.  The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man.

Authors:  M C Carey; D M Small
Journal:  J Clin Invest       Date:  1978-04       Impact factor: 14.808

4.  Evidence for a potent nucleating factor in the gallbladder bile of patients with cholesterol gallstones.

Authors:  M J Burnstein; R G Ilson; C N Petrunka; R D Taylor; S M Strasberg
Journal:  Gastroenterology       Date:  1983-10       Impact factor: 22.682

5.  Nucleation of cholesterol monohydrate crystals from hepatic and gall-bladder bile of patients with cholesterol gall stones.

Authors:  S H Gollish; M J Burnstein; R G Ilson; C N Petrunka; S M Strasberg
Journal:  Gut       Date:  1983-09       Impact factor: 23.059

6.  Structural aspects of bile salt-lecithin mixed micelles.

Authors:  K Müller
Journal:  Hepatology       Date:  1984 Sep-Oct       Impact factor: 17.425

7.  Cholesterol crystals and the formation of cholesterol gallstones.

Authors:  A Sedaghat; S M Grundy
Journal:  N Engl J Med       Date:  1980-06-05       Impact factor: 91.245

8.  Cholesterol solubility in bile. Evidence that supersaturated bile is frequent in healthy man.

Authors:  R T Holzbach; M Marsh; M Olszewski; K Holan
Journal:  J Clin Invest       Date:  1973-06       Impact factor: 14.808

9.  The role of calcium in the pathogenesis of gallstones: Ca++ electrode studies of model bile salt solutions and other biologic systems. With an hypothesis on structural requirements for Ca++ binding to proteins and bile acids.

Authors:  E W Moore
Journal:  Hepatology       Date:  1984 Sep-Oct       Impact factor: 17.425

10.  Nucleation time: a key factor in the pathogenesis of cholesterol gallstone disease.

Authors:  K R Holan; R T Holzbach; R E Hermann; A M Cooperman; W J Claffey
Journal:  Gastroenterology       Date:  1979-10       Impact factor: 22.682
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