Literature DB >> 4041854

Norepinephrine stimulates serotonin secretion from rat pineal glands, in vitro.

R F Walker, V J Aloyo.   

Abstract

The purpose of this study was to determine if serotonin (5-HT) is secreted by the pineal gland and also to define the parameters of its secretion. After radiolabelling the endogenous 5-HT pool, individual pineal glands were placed within perifusion chambers and stimulated with norepinephrine (NE). [3H]5-HT was rapidly released within 1 min of stimulation and secretion continued throughout the period of exposure to NE. The findings suggest that 5-HT, in addition to melatonin, is a hormone of the pineal gland.

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Year:  1985        PMID: 4041854     DOI: 10.1016/0006-8993(85)91177-1

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  5 in total

1.  Diurnal variation in norepinephrine-stimulated release of pineal serotonin in vitro.

Authors:  B Benson; W D Reynolds; D M Burns; C A Leadem
Journal:  J Neural Transm Gen Sect       Date:  1989

Review 2.  The rhythm and blues of gene expression in the rodent pineal gland.

Authors:  Magdalena Karolczak; Horst-Werner Korf; Jörg H Stehle
Journal:  Endocrine       Date:  2005-07       Impact factor: 3.633

3.  Serotonin modulates melatonin synthesis as an autocrine neurotransmitter in the pineal gland.

Authors:  Bo Hyun Lee; Bertil Hille; Duk-Su Koh
Journal:  Proc Natl Acad Sci U S A       Date:  2021-10-26       Impact factor: 11.205

4.  Melatonin Synthesis: Acetylserotonin O-Methyltransferase (ASMT) Is Strongly Expressed in a Subpopulation of Pinealocytes in the Male Rat Pineal Gland.

Authors:  Martin F Rath; Steven L Coon; Fernanda G Amaral; Joan L Weller; Morten Møller; David C Klein
Journal:  Endocrinology       Date:  2016-03-07       Impact factor: 4.736

5.  Transplantation of the rat pineal organ to the brain: pinealocyte differentiation and innervation.

Authors:  T Nonaka; M Araki; H Kimura; I Nagatsu; F Satoh; T Masuzawa
Journal:  Cell Tissue Res       Date:  1990-05       Impact factor: 5.249

  5 in total

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