| Literature DB >> 4041479 |
V A Kosykh, S N Preobrazhensky, I V Fuki, O E Zaikina, V P Tsibulsky, V S Repin, V N Smirnov.
Abstract
During a 5 day cultivation of human hepatocytes in a primary culture the secretion of apolipoprotein B was measured by enzyme-linked immunosorbent assay. Density-gradient ultracentrifugation demonstrated that the majority of the secreted apolipoprotein B was associated with the very-low-density lipoprotein fraction. Exposure of the cells to cholesterol (5-100 micrograms/ml) resulted in a dose-dependent increase in apolipoprotein B secretion rate.Entities:
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Year: 1985 PMID： 4041479 DOI： 10.1016/0005-2760(85)90143-2
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002