| Literature DB >> 4041402 |
M G Chapman, M Dowsett, C J Dewhurst, S L Jeffcoate.
Abstract
The clinical efficacy of a combination of spironolactone and an oral contraceptive pill (Conova 30) was assessed in 23 patients presenting with hirsutism of whom 20 completed 6 months of treatment. Of the 20 patients, 16 showed improvement on objective (Ferriman & Gallwey hair score) and subjective assessment. Serum levels of androgens (testosterone, androstenedione and 17-hydroxy progesterone) were suppressed and sex hormone binding globulins were elevated. Nausea was the only significant side effect.Entities:
Keywords: Androgens; Biology; Clinical Research; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Methods; Diseases; Drugs; Endocrine System; Family Planning; Hirsutism; Hormones; Oral Contraceptives; Physiology; Research Methodology; Signs And Symptoms; Treatment
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Year: 1985 PMID： 4041402 DOI： 10.1111/j.1471-0528.1985.tb03081.x
Source DB: PubMed Journal: Br J Obstet Gynaecol ISSN： 0306-5456