Literature DB >> 4040582

[Intraperitoneal cisplatin in peritoneal carcinomatosis patients].

M Toi, T Shiramizu, T Yonemura, T Ezaki, N Oka, T Yoshida, H Tsurumaru.   

Abstract

Cisplatin (100 mg) was given by intraperitoneal infusion to 23 patients with peritoneal carcinomatosis. Eighteen patients had gastric cancer, and five had colorectal cancer. The effects of this therapy were as follows. 1) In gastric cancer patients, the mean survival period was 11.0 months. The cumulative survival rate was superior at the level of statistical significance in comparison with controls. 2) The side effects of this agent given intraperitoneally were mild. In particular, nausea was slightly less than with intravesicular or intraarterial infusion.

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Year:  1985        PMID: 4040582

Source DB:  PubMed          Journal:  Gan No Rinsho        ISSN: 0021-4949


  2 in total

Review 1.  Then and now: cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC), a historical perspective.

Authors:  Madalyn G Neuwirth; H Richard Alexander; Giorgos C Karakousis
Journal:  J Gastrointest Oncol       Date:  2016-02

2.  [Effective treatment of peritoneal carcinosis by intraperitoneal cis-diamminedichloroplatinum (c-DDP) administration with systemic sodium thiosulfate protection. Clinical results and pharmacokinetics].

Authors:  H Rückle; G Ehninger; F Jakob; K Wilms
Journal:  Klin Wochenschr       Date:  1986-05-15
  2 in total

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