| Literature DB >> 4040550 |
A Veronesi, V Zagonel, U Tirelli, E Galligioni, S Tumolo, L Barzan, M Lorenzini, R Comoretto, E Grigoletto.
Abstract
From November 1981 to February 1983, 64 patients with advanced head and neck squamous carcinoma were randomly treated with either high-dose (120 mg/m2) or low-dose (60 mg/m2) cisplatin. Of the 62 eligible patients, 59 were evaluable: the response rate observed in patients receiving high-dose and low-dose cisplatin was 16.1% and 17.8%, respectively. Survival was superimposable in the two treatment arms. No evidence of dose dependency of cisplatin activity in advanced head and neck squamous carcinoma was noted in this randomized trial.Entities:
Mesh:
Substances:
Year: 1985 PMID: 4040550 DOI: 10.1200/JCO.1985.3.8.1105
Source DB: PubMed Journal: J Clin Oncol ISSN: 0732-183X Impact factor: 44.544