Literature DB >> 4039006

Increased frequency of lymphocytic mitotic non-disjunction in recurrent spontaneous aborters.

R C Juberg, J Knops, P N Mowrey.   

Abstract

Hypermodal chromosomal spreads occurred significantly more frequently in lymphocytes from couples with recurrent spontaneous abortion than from comparison populations. Previously, we reported a similarly increased frequency in couples with aneuploid offspring. Considering the frequency of aneuploidy among first trimester spontaneous abortions, we suggest that there may be a sub-population of persons predisposed to non-disjunction among couples with reproductive wastage.

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Year:  1985        PMID： 4039006      PMCID： PMC1049374          DOI： 10.1136/jmg.22.1.32

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  8 in total

1.  High resolution of human chromosomes.

Authors:  J J Yunis
Journal:  Science       Date:  1976-03-26       Impact factor: 47.728

2.  A rapid banding technique for human chromosomes.

Authors:  M Seabright
Journal:  Lancet       Date:  1971-10-30       Impact factor: 79.321

3.  Socioeconomic and reproductive characteristics of the parents of patients with the G1-trisomy syndrome.

Authors:  R C Juberg; C R Goshen; F G Sholte
Journal:  Soc Biol       Date:  1973-12

4.  Genetic services in the United States.

Authors:  S J Sepe; J S Marks; G P Oakley; A F Manley
Journal:  JAMA       Date:  1982-10-08       Impact factor: 56.272

5.  Paternal age and Down syndrome in British Columbia.

Authors:  E B Hook; P K Cross; S H Lamson; R R Regal; P A Baird; S H Uh
Journal:  Am J Hum Genet       Date:  1981-01       Impact factor: 11.025

6.  Leukocyte chromosomes from parents of cytogenetically abnormal offspring: preliminary observations.

Authors:  R Stallard; N R Haney; P A Frank; P Styron; R C Juberg
Journal:  Cytogenet Cell Genet       Date:  1981

7.  Anatomic and chromosomal anomalies in 639 spontaneous abortuses.

Authors:  T Kajii; A Ferrier; N Niikawa; H Takahara; K Ohama; S Avirachan
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

8.  Down syndrome and recent demographic trends in Manitoba.

Authors:  J A Evans; A G Hunter; J L Hamerton
Journal:  J Med Genet       Date:  1978-02       Impact factor: 6.318
  8 in total
  3 in total

1.  Replication asynchrony increases in women at risk for aneuploid offspring.

Authors:  A Amiel; O Reish; E Gaber; I Kedar; R Diukman; M Fejgin
Journal:  Chromosome Res       Date:  2000       Impact factor: 5.239

2.  The frequency of aneuploidy in cultured lymphocytes is correlated with age and gender but not with reproductive history.

Authors:  G P Nowinski; D L Van Dyke; B C Tilley; G Jacobsen; V R Babu; M J Worsham; G N Wilson; L Weiss
Journal:  Am J Hum Genet       Date:  1990-06       Impact factor: 11.025

3.  Increased spindle resistance to antimicrotubule agents in women of high risk for meiotic nondisjunction.

Authors:  A Dotan; L Avivi
Journal:  Hum Genet       Date:  1986-07       Impact factor: 4.132
  3 in total

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