Literature DB >> 4038299

Tetrameric alkaline phosphatase in human liver plasma membranes.

A Chakrabartty, R A Stinson.   

Abstract

Molecular weights of native membrane-bound alkaline phosphatase released by butanol and by nonionic detergents were more than twice that of the purified dimeric enzyme. Alkaline phosphatase released by phosphatidylinositol-specific phospholipase-C was of both high and low molecular weight: the former was a protomer of a single protein of the same molecular size as monomeric alkaline phosphatase. We conclude that the membrane-bound enzyme is probably a tetramer.

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Year:  1985        PMID： 4038299     DOI： 10.1016/0006-291x(85)91806-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  4 in total

1.  Conversion of human placental alkaline phosphatase from a high Mr form to a low Mr form during butanol extraction. An investigation of the role of endogenous phosphoinositide-specific phospholipases.

Authors:  A S Malik; M G Low
Journal:  Biochem J       Date:  1986-12-01       Impact factor: 3.857

2.  Human tissue non-specific alkaline phosphatases: sugar-moiety-induced enzymic and antigenic modulations and genetic aspects.

Authors:  O Nosjean; I Koyama; M Goseki; B Roux; T Komoda
Journal:  Biochem J       Date:  1997-01-15       Impact factor: 3.857

3.  Correlation between alkaline and acid phosphatase activities and age-related osteopenia in murine vertebrae.

Authors:  B Bar-Shira-Maymon; R Coleman; E Steinhagen-Thiessen; M Silbermann
Journal:  Calcif Tissue Int       Date:  1989-02       Impact factor: 4.333

4.  High lateral mobility of endogenous and transfected alkaline phosphatase: a phosphatidylinositol-anchored membrane protein.

Authors:  M Noda; K Yoon; G A Rodan; D E Koppel
Journal:  J Cell Biol       Date:  1987-10       Impact factor: 10.539
  4 in total

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