Literature DB >> 4038273

Inositol phosphate formation in fMet-Leu-Phe-stimulated human neutrophils does not require an increase in the cytosolic free Ca2+ concentration.

F Di Virgilio, L M Vicentini, S Treves, G Riz, T Pozzan.   

Abstract

The accumulation of inositol phosphates in myo-[3H]inositol-labelled human neutrophils stimulated with the chemotactic peptide fMet-Leu-Phe was measured. The challenge with the chemotactic peptide caused the generation of inositol monophosphate (InsP), inositol bisphosphate (InsP2) and inositol trisphosphate (InsP3). The formation of the three inositol phosphates followed a differential time course: InsP3 accumulated very rapidly and transiently, whereas InsP increased steadily for more than 2 min. Inositol phosphate formation was only partially decreased by procedures which prevented the fMet-Leu-Phe-dependent increase of cytosolic free Ca2+ concentration.

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Year:  1985        PMID： 4038273      PMCID： PMC1145068          DOI： 10.1042/bj2290361

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  31 in total

1.  Relationship between hormonal activation of phosphatidylinositol hydrolysis, fluid secretion and calcium flux in the blowfly salivary gland.

Authors:  J N Fain; M J Berridge
Journal:  Biochem J       Date:  1979-01-15       Impact factor: 3.857

2.  The relationship of calcium to receptor-controlled stimulation of phosphatidylinositol turnover. Effects of acetylcholine, adrenaline, calcium ions, cinchocaine and a bivalent cation ionophore on rat parotid-gland fragments.

Authors:  L M Jones; R H Michell
Journal:  Biochem J       Date:  1975-06       Impact factor: 3.857

Review 3.  The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions.

Authors:  R H Michell; C J Kirk; L M Jones; C P Downes; J A Creba
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1981-12-18       Impact factor: 6.237

4.  Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands.

Authors:  M J Berridge; C P Downes; M R Hanley
Journal:  Biochem J       Date:  1982-09-15       Impact factor: 3.857

5.  Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

Authors:  R Y Tsien; T Pozzan; T J Rink
Journal:  J Cell Biol       Date:  1982-08       Impact factor: 10.539

6.  The dependence on Ca2+ of phosphatidylinositol breakdown and enzyme secretion in rabbit neutrophils stimulated by formylmethionyl-leucylphenylalanine or ionomycin.

Authors:  S Cockcroft; J P Bennett; B D Gomperts
Journal:  Biochem J       Date:  1981-12-15       Impact factor: 3.857

7.  Chemotactic factor causes rapid decreases in phosphatidylinositol,4,5-bisphosphate and phosphatidylinositol 4-monophosphate in rabbit neutrophils.

Authors:  M Volpi; R Yassin; P H Naccache; R I Sha'afi
Journal:  Biochem Biophys Res Commun       Date:  1983-05-16       Impact factor: 3.575

8.  Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol.

Authors:  M J Berridge
Journal:  Biochem J       Date:  1983-06-15       Impact factor: 3.857

9.  Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides.

Authors:  M J Berridge; R M Dawson; C P Downes; J P Heslop; R F Irvine
Journal:  Biochem J       Date:  1983-05-15       Impact factor: 3.857

10.  Requirement for calcium ions in acetylcholine-stimulated phosphodiesteratic cleavage of phosphatidyl-myo-inositol 4,5-bisphosphate in rabbit iris smooth muscle.

Authors:  R A Akhtar; A A Abdel-Latif
Journal:  Biochem J       Date:  1980-12-15       Impact factor: 3.857
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  27 in total

1.  How far does phospholipase C activity depend on the cell calcium concentration? A study in intact cells.

Authors:  D Renard; J Poggioli; B Berthon; M Claret
Journal:  Biochem J       Date:  1987-04-15       Impact factor: 3.857

2.  Internalization pathway of C3b receptors in human neutrophils and its transmodulation by chemoattractant receptors stimulation.

Authors:  J L Carpentier; D P Lew; J P Paccaud; R Gil; B Iacopetta; M Kazatchkine; O Stendahl; T Pozzan
Journal:  Cell Regul       Date:  1991-01

3.  The dependence on Ca2+ of the guanine-nucleotide-activated polyphosphoinositide phosphodiesterase in neutrophil plasma membranes.

Authors:  S Cockcroft
Journal:  Biochem J       Date:  1986-12-01       Impact factor: 3.857

Review 4.  Fluorescence and bioluminescence measurement of cytoplasmic free calcium.

Authors:  P H Cobbold; T J Rink
Journal:  Biochem J       Date:  1987-12-01       Impact factor: 3.857

5.  Relationship of phosphatidylinositol bisphosphate hydrolysis to calcium mobilization and functional activation in fluoride-treated neutrophils.

Authors:  D English; D J Debono; T G Gabig
Journal:  J Clin Invest       Date:  1987-07       Impact factor: 14.808

6.  Leukotriene B4 stimulation of phagocytes results in the formation of inositol 1,4,5-trisphosphate. A second messenger for Ca2+ mobilization.

Authors:  T Andersson; W Schlegel; A Monod; K H Krause; O Stendahl; D P Lew
Journal:  Biochem J       Date:  1986-12-01       Impact factor: 3.857

7.  Phospholipid metabolism in human neutrophils activated by N-formyl-methionyl-leucyl-phenylalanine. Degranulation is not required for release of arachidonic acid: studies with neutrophils and neutrophil-derived cytoplasts.

Authors:  E M Wynkoop; M J Broekman; H M Korchak; A J Marcus; G Weissmann
Journal:  Biochem J       Date:  1986-06-15       Impact factor: 3.857

8.  Escherichia coli hemolysin is a potent inductor of phosphoinositide hydrolysis and related metabolic responses in human neutrophils.

Authors:  F Grimminger; U Sibelius; S Bhakdi; N Suttorp; W Seeger
Journal:  J Clin Invest       Date:  1991-11       Impact factor: 14.808

9.  Neomycin induces stimulatory and inhibitory effects on leukotriene generation, guanine triphosphatase activity, and actin polymerization within human neutrophils.

Authors:  C Brom; J Brom; W König
Journal:  Immunology       Date:  1992-01       Impact factor: 7.397

10.  Involvement of calcium in modulation of neutrophil function by phorbol esters that activate protein kinase C isotypes and related enzymes.

Authors:  J E Merritt; K E Moores; A T Evans; P Sharma; F J Evans; C H MacPhee
Journal:  Biochem J       Date:  1993-02-01       Impact factor: 3.857
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