[Changes in the cellular reactivity of guinea pigs sensitized with Bacillus thuringiensis].

Changes in the cell-mediated responsiveness of the body under the action of different variants of B. thuringiensis have been studied in experiments on guinea pigs. The data thus obtained indicate that the development of sensitization occurs in the animals, which is manifested by the increase of the sensitivity of leukocytes to the specific allergen and by the increase of the phagocytic activity of peritoneal macrophages. The most pronounced changes in the immune responsiveness of guinea pigs have been observed after the parenteral administration of B. thuringiensis var. galleriae.