Literature DB >> 403610

Scotopic vision deficits in young monkeys exposed to lead.

P J Bushnell, R E Bowman, J R Allen, R J Marlar.   

Abstract

Rhesus monkeys were reared on diets designed to produce blood lead concentrations of 14 (untreated), 55, or 85 micrograms per 100 milliliters for the first year of life. Eighteen months later, blood lead levels were normal in all animals. At this time, however, visual discrimination performance in the 85-microgram group was impaired under dim light relative both to their own performance under bright light and to the performance of the other groups under all light levels used. We interpret these results to reflect a deleterious, enduring impairment of scotopic visual function (night blindness) as a result of early lead intoxication.

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Year:  1977        PMID: 403610     DOI: 10.1126/science.403610

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  8 in total

1.  Distribution of lead and transthyretin in human eyes.

Authors:  J W Eichenbaum; W Zheng
Journal:  J Toxicol Clin Toxicol       Date:  2000

Review 2.  Recognition and management of children with increased lead absorption.

Authors:  J J Chisolm; D Barltrop
Journal:  Arch Dis Child       Date:  1979-04       Impact factor: 3.791

3.  Effects of lead exposure on peripheral nerve in the cynomolgus monkey.

Authors:  D A Purser; K R Berrill; S K Majeed
Journal:  Br J Ind Med       Date:  1983-11

4.  Low lead levels stunt neuronal growth in a reversible manner.

Authors:  H T Cline; S Witte; K W Jones
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-03       Impact factor: 11.205

Review 5.  Behavioral assessment of visual toxicity.

Authors:  H L Evans
Journal:  Environ Health Perspect       Date:  1978-10       Impact factor: 9.031

Review 6.  Human health effects of air pollution.

Authors:  L J Folinsbee
Journal:  Environ Health Perspect       Date:  1993-04       Impact factor: 9.031

7.  Developmental lead exposure induces tactile defensiveness in rhesus monkeys (Macaca mulatta).

Authors:  Colleen F Moore; Lisa L Gajewski; Nellie K Laughlin; Melissa L Luck; Julie A Larson; Mary L Schneider
Journal:  Environ Health Perspect       Date:  2008-05-30       Impact factor: 9.031

8.  Association between Blood Lead Levels and Age-Related Macular Degeneration.

Authors:  Ho Sik Hwang; Seung Bum Lee; Donghyun Jee
Journal:  PLoS One       Date:  2015-08-07       Impact factor: 3.240

  8 in total

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