| Literature DB >> 4035978 |
R C Wardley, S G Norley, P J Wilkinson, S Williams.
Abstract
Intraperitoneal immunization of pigs with anti-African swine fever virus (ASFV) antibody protected them against the effects of challenge with ASFV. This protection, which was exemplified by a reduction in pyrexia and viraemia plus an increased survival time, appeared to be mediated through the effects of complement-dependent antibody-mediated cytotoxicity (CDAC) or antibody dependent cell mediated cytotoxicity (ADCC). Experiments suggested that the reduction in viraemia was associated with complement lysis whereas protection was conferred by ADCC.Entities:
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Year: 1985 PMID: 4035978 DOI: 10.1016/0165-2427(85)90071-6
Source DB: PubMed Journal: Vet Immunol Immunopathol ISSN: 0165-2427 Impact factor: 2.046