Literature DB >> 4035085

Pharmacokinetics of flunixin meglumine in the cow.

G E Hardee, J A Smith, S J Harris.   

Abstract

Plasma levels of flunixin were measured in heifers after a single intravenous injection (1.1 mg kg-1), using high performance liquid chromatography. Plasma concentration versus time curves were best described by a two compartment model. The distribution phase (alpha) half-life was 0.294 hours, the elimination phase (beta) half-life was 8.12 hours and the volume of distribution was 1050 ml kg-1.

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Year:  1985        PMID: 4035085

Source DB:  PubMed          Journal:  Res Vet Sci        ISSN: 0034-5288            Impact factor:   2.534


  4 in total

1.  The behavioral assessment and alleviation of pain associated with castration in beef calves treated with flunixin meglumine and caudal lidocaine epidural anesthesia with epinephrine.

Authors:  Jan M Currah; Steven H Hendrick; Joseph M Stookey
Journal:  Can Vet J       Date:  2009-04       Impact factor: 1.008

2.  The influence of flunixin on the response to Salmonella typhimurium endotoxin in calves.

Authors:  J Luthman; H Kindahl; S O Jacobsson
Journal:  Acta Vet Scand       Date:  1989       Impact factor: 1.695

3.  The use of intradermal carrageenan in calves to estimate the dose of oxindanac, a nonsteroidal anti-inflammatory drug.

Authors:  J N King
Journal:  Can J Vet Res       Date:  1993-10       Impact factor: 1.310

4.  Analgesic effects of intravenous flunixin and intrafunicular lidocaine or their combination for castration of lambs.

Authors:  Paola Straticò; Vincenzo Varasano; Riccardo Suriano; Massimo Mariscoli; Domenico Robbe; Melania Giammarco; Giorgio Vignola; Lucio Petrizzi
Journal:  Vet Rec Open       Date:  2018-07-06
  4 in total

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