| Literature DB >> 403284 |
A Mooradian, P E Dupont, A G Hlavec, M D Aceto, J Pearl.
Abstract
3-Dimethylamino-1,2,3,4-tetrahydrocarbazole, a structurally modified tryptamine, prevented amphetamine-induced stereotyped behavior in rats and prevented reserpine-induced ptosis in mice. Further study of this compound and a number of substituted derivatives indicated that either imipramine-like or chlorpromazine-like profiles were obtainable by changing substituents and their positions.Entities:
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Year: 1977 PMID： 403284 DOI： 10.1021/jm00214a005
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446