Literature DB >> 4031006

Consideration of covariates and stratification in sample size determination for survival time studies.

M Palta, S B Amini.   

Abstract

Sample size determination for survival time studies is discussed, taking into account stratification. We present formulas and tables which also apply in the case of multicenter clinical trials. In addition, the same method is used to estimate the sample size requirement when a covariate is grouped into strata. Simulation studies compare the results to covariate adjustment by the Cox proportional hazards model.

Mesh：

Year:  1985        PMID： 4031006     DOI： 10.1016/0021-9681(85)90123-7

Source DB:  PubMed          Journal:  J Chronic Dis        ISSN： 0021-9681


  2 in total

1.  Frailty impairs the feasibility of induction therapy but not of maintenance therapy in elderly myeloma patients: final results of the German Maintenance Study (GERMAIN).

Authors:  Annamaria Brioli; Kirsi Manz; Markus Pfirrmann; Mathias Hänel; Andreas Christoph Schwarzer; Gabriele Prange-Krex; Christian Fabisch; Stefan Knop; Thomas Illmer; Beate Krammer-Steiner; Andreas Hochhaus; Marie von Lilienfeld-Toal; Lars-Olof Mügge
Journal:  J Cancer Res Clin Oncol       Date:  2019-12-02       Impact factor: 4.553

2.  Modelling the effects of standard prognostic factors in node-positive breast cancer. German Breast Cancer Study Group (GBSG).

Authors:  W Sauerbrei; P Royston; H Bojar; C Schmoor; M Schumacher
Journal:  Br J Cancer       Date:  1999-04       Impact factor: 7.640
  2 in total

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