Literature DB >> 403098

Marked instability of character of cloned epithelial cells.

H P Schnebli, M Burger, F F Strasser, E Suter.   

Abstract

Cell lines derived from 7,12-dimethylbenzanthracene-induced rat mammary carcinomas show a marked drift in properties when cultured in vitro. The following characteristics alter progressively with the number of passages: cloning efficiency, requirement for hydrocortisone, requirement for fetal sera, growth response to conditioning factor(s) and ease of detachment from the culture vessel by trypsinization.

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Year:  1977        PMID: 403098     DOI: 10.1159/000162855

Source DB:  PubMed          Journal:  Exp Cell Biol        ISSN: 0304-3568


  2 in total

1.  Growth factor interactions between mouse mammary cell lines cocultured in collagen gels.

Authors:  S Hamner; W Jones; J R Starkey; H L Hosick
Journal:  In Vitro Cell Dev Biol       Date:  1989-12

2.  Clones of MRC-C cells may be superior to the parent line for the culture of 229E-like strains of human respiratory coronavirus.

Authors:  R J Phillpotts
Journal:  J Virol Methods       Date:  1983-05       Impact factor: 2.014

  2 in total

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