Literature DB >> 403069

Suppression of prolactin and thyrotropin secretion in the rat by antiserum to thyrotropin-releasing hormone.

Y Koch, G Goldhaber, I Fireman, U Zor, J Shani, E Tal.   

Abstract

Administration of antiserum to synthetic thyrotropin-releasing hormone (TRH) to male and female rats cause a 50% and a 70% suppression in serum levels of prolactin and thyrotropin, respectively, as compared with controls injected with normal rabbit serum. The degree of suppression was similar in diestrous and proestrous female rats and in male rats. These findings support the view that, in addition to its original designation, TRH also has a physiological role in regulating release of pituitary prolactin.

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Year:  1977        PMID: 403069     DOI: 10.1210/endo-100-5-1476

Source DB:  PubMed          Journal:  Endocrinology        ISSN: 0013-7227            Impact factor:   4.736


  3 in total

1.  Thyrotropin-releasing hormone is not required for thyrotropin secretion in the perinatal rat.

Authors:  T Theodoropoulos; L E Braverman; A G Vagenakis
Journal:  J Clin Invest       Date:  1979-04       Impact factor: 14.808

2.  TRH: pathophysiologic and clinical implications.

Authors:  C R Pickardt; P C Scriba
Journal:  Acta Neurochir (Wien)       Date:  1985       Impact factor: 2.216

3.  The physiological role of thyrotropin-releasing hormone in the regulation of thyroid-stimulating hormone and prolactin secretion in the rat.

Authors:  A R Harris; D Christianson; M S Smith; S L Fang; L E Braverman; A G Vagenakis
Journal:  J Clin Invest       Date:  1978-02       Impact factor: 14.808

  3 in total

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