Literature DB >> 4030623

Establishment of a continuous cell line from fibrotic schistosomal granulomas in mice livers.

R Borojevic, A N Monteiro, S A Vinhas, G B Domont, P A Mourão, H Emonard, G Grimaldi, J A Grimaud.   

Abstract

A continuous murine cell line (GRX) was obtained from fibrotic granulomas induced in C3H/HeN mice liver by experimental infection with Schistosoma mansoni. This anchorage-dependent line produces composite connective tissue/extracellular matrix, displays morphological characteristics of myofibroblasts, and can, under appropriate conditions, accumulate fat droplets. GRX cells produce viral particles of retrovirus type. We consider GRX cell line to be representative of liver connective tissue cells, responsible for fibroplasia in liver fibrotic and granulomatous reactions.

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Mesh：

Year:  1985        PMID： 4030623     DOI： 10.1007/bf02623469

Source DB:  PubMed          Journal:  In Vitro Cell Dev Biol        ISSN： 0883-8364


  20 in total

Review 1.  The smooth muscle cell in culture.

Authors:  J Chamley-Campbell; G R Campbell; R Ross
Journal:  Physiol Rev       Date:  1979-01       Impact factor: 37.312

2.  Relationship between connective tissue cells and fibronectin in a sequential model of experimental hepatic fibrosis.

Authors:  G Cenacchi; G Ballardini; L Badiali De Giorgi; C A Busachi; M Del Rosso; F B Bianchi; G Biagini; R Laschi
Journal:  Virchows Arch B Cell Pathol Incl Mol Pathol       Date:  1983

3.  Sulfated glycosaminoglycans synthesized by fibroblast, smooth muscle and endothelium-like cells grown in culture.

Authors:  P A Mourão; S Pillai; P V Donnelly
Journal:  Cell Differ       Date:  1983-02

Review 4.  Fibrosis of the liver: the role of the ectoskeleton.

Authors:  H Popper; G R Martin
Journal:  Prog Liver Dis       Date:  1982

5.  The implantation of sepharose beads in mouse livers as an aid in the study of hepatic schistosomal fibrosis.

Authors:  E A van Marck; S Stocker; J A Grimaud; L Kestens; P L Gigase; A M Deelder
Journal:  Experientia       Date:  1980-09-15

6.  Connective matrix organization in human pulmonary fibrosis. Collagen polymorphism analysis in fibrotic deposits by immunohistological methods.

Authors:  C Takiya; S Peyrol; J F Cordier; J A Grimaud
Journal:  Virchows Arch B Cell Pathol Incl Mol Pathol       Date:  1983

7.  Granulomatous inflammation in normal and athymic mice infected with schistosoma mansoni: an ultrastructural study.

Authors:  W L Epstein; K Fukuyama; K Danno; E Kwan-Wong
Journal:  J Pathol       Date:  1979-04       Impact factor: 7.996

8.  Fibroblast stimulation in schistosomiasis. II. Functional and biochemical characteristics of egg granuloma-derived fibroblast-stimulating factor.

Authors:  D J Wyler; L J Rosenwasser
Journal:  J Immunol       Date:  1982-10       Impact factor: 5.422

9.  The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers.

Authors:  R Ross
Journal:  J Cell Biol       Date:  1971-07       Impact factor: 10.539

10.  Collagen substrata for studies on cell behavior.

Authors:  T Elsdale; J Bard
Journal:  J Cell Biol       Date:  1972-09       Impact factor: 10.539
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  18 in total

1.  Growth arrest and decrease of alpha-SMA and type I collagen expression by palmitic acid in the rat hepatic stellate cell line PAV-1.

Authors:  Armand Abergel; Vincent Sapin; Nicolas Dif; Christophe Chassard; Claude Darcha; Julie Marcand-Sauvant; Brigitte Gaillard-Martinie; Edmond Rock; Pierre Dechelotte; Patrick Sauvant
Journal:  Dig Dis Sci       Date:  2006-04-27       Impact factor: 3.199

Review 2.  Vitamin A and lipid metabolism: relationship between hepatic stellate cells (HSCs) and adipocytes.

Authors:  Patrick Sauvant; Maud Cansell; Claude Atgié
Journal:  J Physiol Biochem       Date:  2011-05-31       Impact factor: 4.158

3.  Lipid metabolism during in vitro induction of the lipocyte phenotype in hepatic stellate cells.

Authors:  C P Vicente; R M Guaragna; R Borojevic
Journal:  Mol Cell Biochem       Date:  1997-03       Impact factor: 3.396

4.  In vitro induction of the fat-storing phenotype in a liver connective tissue cell line-GRX.

Authors:  R Borojevic; R M Guaragna; R Margis; H S Dutra
Journal:  In Vitro Cell Dev Biol       Date:  1990-04

5.  Development and characterization of a rainbow trout liver cell line expressing cytochrome P450-dependent monooxygenase activity.

Authors:  L E Lee; J H Clemons; D G Bechtel; S J Caldwell; K B Han; M Pasitschniak-Arts; D D Mosser; N C Bols
Journal:  Cell Biol Toxicol       Date:  1993 Jul-Sep       Impact factor: 6.691

6.  Resveratrol inhibits cell growth by inducing cell cycle arrest in activated hepatic stellate cells.

Authors:  Izabel C Souza; Leo Anderson M Martins; Barbara P Coelho; Ivana Grivicich; Regina M Guaragna; Carmem Gottfried; Radovan Borojevic; Fátima Costa Rodrigues Guma
Journal:  Mol Cell Biochem       Date:  2008-05-04       Impact factor: 3.396

7.  Effect of pentoxifylline on arachidonic acid metabolism, neutral lipid synthesis and accumulation during induction of the lipocyte phenotype by retinol in murine hepatic stellate cell.

Authors:  Carla C A Cardoso; Ernani R Paviani; Lavínia A Cruz; Fátima C R Guma; Radovan Borojevic; Regina M Guaragna
Journal:  Mol Cell Biochem       Date:  2003-12       Impact factor: 3.396

8.  Lycopene isomerisation and storage in an in vitro model of murine hepatic stellate cells.

Authors:  Anderson J Teodoro; Daniel Perrone; Renata B Martucci; Radovan Borojevic
Journal:  Eur J Nutr       Date:  2009-06-17       Impact factor: 5.614

9.  Retinol uptake and metabolism, and cellular retinol binding protein expression in an in vitro model of hepatic stellate cells.

Authors:  C P Vicente; V A Fortuna; R Margis; L Trugo; R Borojevic
Journal:  Mol Cell Biochem       Date:  1998-10       Impact factor: 3.396

Review 10.  Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver.

Authors:  Scott L Friedman
Journal:  Physiol Rev       Date:  2008-01       Impact factor: 37.312
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