Literature DB >> 4030545

Synthesis and preliminary in-vitro profile of Sch 34343--a new penem antibacterial agent.

A K Ganguly, A Afonso, V M Girijavallabhan, S McCombie.   

Abstract

Sch 34343, a new penem antibiotic, has been synthesized by several routes and found to be highly active against both aerobic and anaerobic Gram-positive and Gram-negative organisms (except Pseudomonas). It has excellent beta-lactamase stability and is bactericidal. The synthetic routes to Sch 34343 and its in-vitro activity compared with other structurally related penems are discussed.

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Year:  1985        PMID: 4030545     DOI: 10.1093/jac/15.suppl_c.1

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  3 in total

1.  In vitro activity of CGP 31608, a new penem.

Authors:  R Wise; J M Andrews; L J Piddock
Journal:  Antimicrob Agents Chemother       Date:  1987-02       Impact factor: 5.191

2.  beta-Lactam resistance of motile Aeromonas isolates from clinical and environmental sources.

Authors:  K Morita; N Watanabe; S Kurata; M Kanamori
Journal:  Antimicrob Agents Chemother       Date:  1994-02       Impact factor: 5.191

3.  In vitro activity and beta-lactamase stability of a new penem, CGP 31608.

Authors:  H C Neu; N X Chin; N M Neu
Journal:  Antimicrob Agents Chemother       Date:  1987-04       Impact factor: 5.191

  3 in total

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