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Literature DB >> 4029551

Improvement of endoscopic and histologic findings of AA-type gastrointestinal amyloidosis by treatment with dimethyl sulfoxide and prednisolone.

A Takahashi, J Matsumoto, S Nishimura, N Tanida, S Imura, T Isobe, T Shimoyama.

Abstract

We report the successful treatment of gastrointestinal amyloidosis with dimethyl sulfoxide. A 37 year-old man with adult-onset Still's disease suffered from diarrhea. Upper and lower gastrointestinal endoscopy revealed edematous mucosa, white patches, erosions and bleeding and amyloid deposits were demonstrated in biopsy specimens. After a period of 3 months dimethyl sulfoxide and prednisolone therapy, improvement in the endoscopic appearance of the gastrointestinal tract was observed. Amyloid deposits in biopsy specimens were reduced in the stomach and negative in the large intestine.

Entities: Chemical Disease Species

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Year: 1985 PMID： 4029551 DOI： 10.1007/bf02776678

Source DB: PubMed Journal: Gastroenterol Jpn ISSN： 0435-1339

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References

9 in total

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Journal: Am J Med Date: 1968-06 Impact factor: 4.965

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Authors: Y Imai; S Himeno; Y Shinomura; T Kuroshima; Y Minami; S Tarui; T Isobe; M Tomita
Journal: Nihon Naika Gakkai Zasshi Date: 1984-09

Improvement of endoscopic and histologic findings of AA-type gastrointestinal amyloidosis by treatment with dimethyl sulfoxide and prednisolone.

Review 1. A clinical analysis of the course and prognosis of forty-two patients with amyloidosis.

2. Deposition of amyloid in the gastrointestinal tract.

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