Literature DB >> 4029397

A monoclonal antibody reacting specifically with ganglioside GD1b in human brain.

P Fredman, S Jeansson, E Lycke, L Svennerholm.   

Abstract

A mouse monoclonal antibody directed against one of the major human brain gangliosides, GD1b, has been produced. The antibody binds specifically to the carbohydrate structure of GD1b as it does not react with structurally related gangliosides like GM1, GD2, GT1b or Fuc-GM1, or any other ganglioside of human brain. The results further indicate that terminal galactose as well as the disialosyl group linked to the inner galactose moiety are involved in binding to the antibody.

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Year:  1985        PMID： 4029397     DOI： 10.1016/0014-5793(85)80834-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  3 in total

1.  In vivo growth conditions suppress the expression of ganglioside GM2 and favour that of lacto series gangliosides in the human glioma D-54MG cell line.

Authors:  P Fredman; C J Wikstrand; J E Månsson; G Reifenberger; S H Bigner; A Rasheed; L Svennerholm; D D Bigner
Journal:  Glycoconj J       Date:  1996-06       Impact factor: 2.916

2.  Herpes simplex virus infection of the human sensory neuron. An electron microscopy study.

Authors:  E Lycke; B Hamark; M Johansson; A Krotochwil; J Lycke; B Svennerholm
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

3.  Production and characterization of serovar-specific monoclonal antibodies to serovars 4, 8, and 9 of Mycobacterium intracellulare.

Authors:  K Nishimori; H Yugi; M Naiki; T Sugimura; Y Tanaka; I Nonomura; Y Yokomizo; S Kubo
Journal:  Infect Immun       Date:  1987-03       Impact factor: 3.441
  3 in total

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