Literature DB >> 4029103

Interaction of alkylmercuric compounds with sodium selenite. II. Metabolism of methylmercuric chloride administered alone and in combination with sodium selenite in rats.

E A Brzeźnicka, J Chmielnicka.   

Abstract

Repeated doses of sodium selenite (Se) were administered to rats receiving repeated (IV or PO) doses of 0.25 or 2.5 mg Hg/kg methylmercuric chloride (Me2(203)Hg). Se (0.5 mg/kg) was observed to alter the distribution of Me203Hg among tissues as well as among subcellular fractions of kidneys and liver. An excess of selenium resulted in a twofold decrease in the mercury content of kidneys and a similar increase in the mercury content of brain.

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Year:  1985        PMID： 4029103      PMCID： PMC1568548          DOI： 10.1289/ehp.60-1568548

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN： 0091-6765            Impact factor:   9.031


  38 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  Interaction of selenium and mercury in the rat.

Authors:  S C Fang
Journal:  Chem Biol Interact       Date:  1977-04       Impact factor: 5.192

Review 3.  The pharmacology of mercury compounds.

Authors:  T W Clarkson
Journal:  Annu Rev Pharmacol       Date:  1972       Impact factor: 13.820

4.  Methyl mercury intoxication in rat kidneys. Functional and pathological changes.

Authors:  R Klein; S P Herman; B C Bullock; F A Talley
Journal:  Arch Pathol       Date:  1973-08

5.  The effect of selenium on the brain uptake of methylmercury.

Authors:  L Magos; M Webb
Journal:  Arch Toxicol       Date:  1977-09-28       Impact factor: 5.153

6.  Comparative study of the sensitivity of virgin and pregnant rats to methylmercury.

Authors:  L Magos; G C Peristianis; T W Clarkson; R T Snowden; M A Majeed
Journal:  Arch Toxicol       Date:  1980-02       Impact factor: 5.153

7.  Effect of selenium on methylmercury binding to subcellular and soluble proteins in rat tissues.

Authors:  R W Chen; V L Lacy; P D Whanger
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1975-10

8.  Studies on the interaction and distribution of selenite, mercuric, methoxyethyl mercuric and methyl mercuric chloride in rats. I. Analysis of brain, liver, kidney and faeces.

Authors:  H Mengel; O Karlog
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1980-01

Review 9.  Factors influencing metabolism and toxicity of metals: a consensus report.

Authors: 
Journal:  Environ Health Perspect       Date:  1978-08       Impact factor: 9.031

10.  Interaction of alkylmercuric compounds with sodium selenite. III. Biotransformation, levels of metallothioneinlike proteins and endogenous copper in some tissues of rats exposed to methyl or ethylmercuric chloride with and without sodium selenite.

Authors:  E A Brzeźnicka; J Chmielnicka
Journal:  Environ Health Perspect       Date:  1985-05       Impact factor: 9.031
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  2 in total

1.  Zinc-selenium interaction in the rat.

Authors:  J Chmielnicka; G Zareba; M Witasik; E Brzeźnicka
Journal:  Biol Trace Elem Res       Date:  1988 Jan-Apr       Impact factor: 3.738

2.  Interaction of alkylmercuric compounds with sodium selenite. III. Biotransformation, levels of metallothioneinlike proteins and endogenous copper in some tissues of rats exposed to methyl or ethylmercuric chloride with and without sodium selenite.

Authors:  E A Brzeźnicka; J Chmielnicka
Journal:  Environ Health Perspect       Date:  1985-05       Impact factor: 9.031
  2 in total

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