Literature DB >> 402877

Dose-related levodopa-induced haemolytic anaemia.

F D Linström, G Liedén, M S Enström.   

Abstract

A 71-year-old white man developed direct antiglobulin positive haemolytic anaemia after 16 months of levodopa therapy for Parkinson's disease. Immunoglobulin G autoantibodies directed against Rh antigens were found in the patient's serum and on his erythrocytes. Reduction of levodopa dosage to one sixth with the aid of a peripheral decarboxylase inhibitor (benserazide) largely eliminated autoimmune haemolysis while maintaining adequate control of neurologic symptoms.

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Year:  1977        PMID： 402877     DOI： 10.7326/0003-4819-86-3-298

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN： 0003-4819            Impact factor:   25.391


  5 in total

1.  Apomorphine-Induced Immune Hemolytic Anemia.

Authors:  Begoña Venegas Pérez; Teresa Arquero Portero; María Soledad Sánchez Fernández; Cici Feliz Feliz; Javier Del Val Fernández; Pedro José García-Ruiz
Journal:  Mov Disord Clin Pract       Date:  2016-06-06

2.  Subcutaneous apomorphine in the treatment of Parkinson's disease.

Authors:  J P Frankel; A J Lees; P A Kempster; G M Stern
Journal:  J Neurol Neurosurg Psychiatry       Date:  1990-02       Impact factor: 10.154

3.  Reversible haemolytic anaemia after levodopa-carbidopa.

Authors:  R M Bernstein
Journal:  Br Med J       Date:  1979-06-02

4.  Identification of protein interfaces between α-synuclein, the principal component of Lewy bodies in Parkinson disease, and the molecular chaperones human Hsc70 and the yeast Ssa1p.

Authors:  Virginie Redeker; Samantha Pemberton; Willy Bienvenut; Luc Bousset; Ronald Melki
Journal:  J Biol Chem       Date:  2012-07-26       Impact factor: 5.157

Review 5.  Movement Disorders and Hematologic Diseases.

Authors:  Roshni Abee Patel; Deborah A Hall; Sheila Eichenseer; Meagan Bailey
Journal:  Mov Disord Clin Pract       Date:  2020-12-29
  5 in total

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