Literature DB >> 4027957

DNA flow cytometry in human testicular cancer.

S D Fosså, E O Pettersen, E Thorud, J E Melvik, S Ous.   

Abstract

DNA flow cytometry revealed aneuploid tumour stemlines in 19 of 20 primary testicular cancers without significant difference of the ploidy values between seminomas and non-seminomas. In 7 of 8 analyzable histograms the S-phase activity was 22-51%. A metastatic mature teratoma had 6% cells in S-phase. These results support the clinical observation that testicular cancer is usually a rapidly growing human tumour. The high percentage of aneuploidy in testicular cancer may be of clinical value in the diagnosis of this malignancy.

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Year:  1985        PMID: 4027957     DOI: 10.1016/0304-3835(85)90092-8

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  2 in total

1.  Automated image analysis DNA cytometry in testicular cancer.

Authors:  R A Bürger; U Witzsch; H Engel; D Potratz; M Stöckle
Journal:  Urol Res       Date:  1994

2.  A randomised phase 2 trial of intensive induction chemotherapy (CBOP/BEP) and standard BEP in poor-prognosis germ cell tumours (MRC TE23, CRUK 05/014, ISRCTN 53643604).

Authors:  Robert A Huddart; Rhian Gabe; Fay H Cafferty; Philip Pollock; Jeff D White; Jonathan Shamash; Michael H Cullen; Sally P Stenning
Journal:  Eur Urol       Date:  2014-07-04       Impact factor: 20.096

  2 in total

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