| Literature DB >> 4027887 |
J J Offerman, H Hollema, J D Elema, H Schraffordt Koops, E G de Vries.
Abstract
A case of fatal acute renal failure during treatment with 1,1-diaminomethyl cyclohexane sulphato platinum II (TNO-6) is reported. Pathologic investigation showed focal tubular necrosis with interstitial infiltration and edema. Despite the development of proteinuria no changes of the glomeruli were found, either by light or electron microscopic investigation. The pathologic changes caused by TNO-6 are similar to those found in renal failure caused by cisplatin (CDDP).Entities:
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Year: 1985 PMID： 4027887 DOI： 10.1002/1097-0142(19851001)56:7<1511::aid-cncr2820560706>3.0.co;2-l
Source DB: PubMed Journal: Cancer ISSN： 0008-543X Impact factor: 6.860