Literature DB >> 4027128

Fenfluramine delays gastric emptying of solid food.

M Horowitz, P J Collins, V Tuckwell, J Vernon-Roberts, D J Shearman.   

Abstract

The effect of a single dose of (+/-)-fenfluramine hydrochloride (40 mg) on gastric emptying of a mixed solid and liquid meal was assessed with a dual isotope scintigraphic technique in eight obese patients. Fenfluramine significantly delayed gastric emptying of solid food (approximately a 15% reduction in the solid linear emptying rate), but had no effect on gastric emptying of liquid.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 4027128      PMCID: PMC1463873          DOI: 10.1111/j.1365-2125.1985.tb02728.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  5 in total

1.  Gastric emptying in normal subjects--a reproducible technique using a single scintillation camera and computer system.

Authors:  P J Collins; M Horowitz; D J Cook; P E Harding; D J Shearman
Journal:  Gut       Date:  1983-12       Impact factor: 23.059

2.  Abnormalities of gastric emptying in obese patients.

Authors:  M Horowitz; P J Collins; D J Cook; P E Harding; D J Shearman
Journal:  Int J Obes       Date:  1983

3.  The gut and preabsorptive satiety.

Authors:  J Gibbs; G P Smith
Journal:  Acta Hepatogastroenterol (Stuttg)       Date:  1978-12

4.  Fenfluramine anorexia: a peripheral locus of action.

Authors:  R F Davies; J Rossi; J Panksepp; N J Bean; A J Zolovick
Journal:  Physiol Behav       Date:  1983-05

5.  Involvement of serotonergic mechanisms in initiation of small intestine cyclic motor events.

Authors:  Y Ruckebusch; T Bardon
Journal:  Dig Dis Sci       Date:  1984-06       Impact factor: 3.199

  5 in total
  2 in total

1.  Orocecal transit delay in obese patients.

Authors:  G Basilisco; G Camboni; A Bozzani; P Vita; S Doldi; P A Bianchi
Journal:  Dig Dis Sci       Date:  1989-04       Impact factor: 3.199

Review 2.  Gastrointestinal morbidity in obesity.

Authors:  Andres Acosta; Michael Camilleri
Journal:  Ann N Y Acad Sci       Date:  2014-03-06       Impact factor: 5.691

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.