Literature DB >> 402691

Lysis of human cultured lymphoblastoid cells by cell-induced activation of the properdin pathway.

A N Theofilopoulos, L H Perrin.   

Abstract

Human cultured lymphoblastoid cells incubated in normal human serum activate the properdin complement pathway without antibody. However, only cells bearing C3b immune adherence receptors bind components of the properdin complement pathway and undergo lysis. A similar surveillance mechanism may exist in man to limit growth of malignant B cells bearing C3b immune adherence receptors.

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Year:  1977        PMID： 402691     DOI： 10.1126/science.402691

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Autosomal locus regulates inverse relationship between sialic acid content and capacity of mouse erythrocytes to activate human alternative complement pathway.

Authors:  U E Nydegger; D T Fearon; K F Austen
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

2.  Persistent complement activation on tumor cells in breast cancer.

Authors:  F Niculescu; H G Rus; M Retegan; R Vlaicu
Journal:  Am J Pathol       Date:  1992-05       Impact factor: 4.307

3.  Antibody-independent complement activation by a subpopulation of mitogen-induced human T lymphoblasts.

Authors:  M J Martin; J Vega; C Gutiérrez
Journal:  Immunology       Date:  1980-11       Impact factor: 7.397

4.  Interaction of desialated guinea pig erythrocytes with the classical and alternative pathways of guinea pig complement in vivo and in vitro.

Authors:  E J Brown; K A Joiner; M M Frank
Journal:  J Clin Invest       Date:  1983-06       Impact factor: 14.808

5.  Regulation by membrane sialic acid of beta1H-dependent decay-dissociation of amplification C3 convertase of the alternative complement pathway.

Authors:  D T Fearon
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

Review 6.  Synthesis of lipids or lipid-containing macromolecules in tumor cells. Relevance to host defense.

Authors:  S H Ohanian
Journal:  Surv Immunol Res       Date:  1983

7.  Inhibition of Epstein-Barr virus (EBV) release from the P3HR-1 Burkitt's lymphoma cell line by a monoclonal antibody against a 200,000 dalton EBV membrane antigen.

Authors:  T Sairenji; P S Reisert; R C Spiro; T Connolly; R E Humphreys
Journal:  J Exp Med       Date:  1985-05-01       Impact factor: 14.307

8.  Surface-associated heparin inhibits zymosan-induced activation of the human alternative complement pathway by augmenting the regulatory action of the control proteins on particle-bound C3b.

Authors:  M D Kazatchkine; D T Fearon; J E Silbert; K F Austen
Journal:  J Exp Med       Date:  1979-11-01       Impact factor: 14.307

Review 9.  Antibody-mediated destruction of virus-infected cells.

Authors:  J G Sissons; M B Oldstone
Journal:  Adv Immunol       Date:  1980       Impact factor: 3.543

Review 10.  Complement, viruses, and virus-infected cells.

Authors:  N R Cooper; G R Nemerow
Journal:  Springer Semin Immunopathol       Date:  1983
  10 in total

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