Literature DB >> 4026574

The octanol/water distribution of mercury compounds.

S Halbach.   

Abstract

Lipophilicity plays an important role in the biological action of mercurials. The distribution of one inorganic and five organic mercury compounds was determined in an n-octanol/water system. Lipophilicity decreased in the order CH3HgCl, bromomercurihydroxypropane, HgCl2, chlormerodrin, p-chloromercuribenzoic acid (PCMB), p-chloromercuriphenylsulfonic acid (PCMBS). The toxicity of mercurials, as reported in the literature, appears to parallel their lipophilicity.

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Year:  1985        PMID： 4026574     DOI： 10.1007/bf00343125

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  8 in total

1.  Methylmercury poisoning in Iraq.

Authors:  F Bakir; S F Damluji; L Amin-Zaki; M Murtadha; A Khalidi; N Y al-Rawi; S Tikriti; H I Dahahir; T W Clarkson; J C Smith; R A Doherty
Journal:  Science       Date:  1973-07-20       Impact factor: 47.728

2.  Maternal-fetal transfer of organic and inorganic mercury via placenta and milk.

Authors:  M M Mansour; N C Dyer; L H Hoffman; A R Schulert; A B Brill
Journal:  Environ Res       Date:  1973-12       Impact factor: 6.498

3.  Storage of mercury at submolar concentrations.

Authors:  M R Greenwood; T W Clarkson
Journal:  Am Ind Hyg Assoc J       Date:  1970 Mar-Apr

4.  A possible physiological uptake mechanism of methylmercury by the marine bloodworm (Glycera dibranchiata).

Authors:  D M Medeiros; L L Cadwell; R L Preston
Journal:  Bull Environ Contam Toxicol       Date:  1980-01       Impact factor: 2.151

5.  Use of distribution coefficients in quantitative structure-activity relationships.

Authors:  R A Scherrer; S M Howard
Journal:  J Med Chem       Date:  1977-01       Impact factor: 7.446

6.  Interaction of mercury with human erythrocytes.

Authors:  R WEED; J EBER; A ROTHSTEIN
Journal:  J Gen Physiol       Date:  1962-01       Impact factor: 4.086

7.  Nephrotic syndrome in adult Africans in Nairobi.

Authors:  R D Barr; P H Rees; P E Cordy; A Kungu; B A Woodger; H M Cameron
Journal:  Br Med J       Date:  1972-04-15

8.  LOCALIZATION OF ERYTHROCYTE MEMBRANE SULFHYDRYL GROUPS ESSENTIAL FOR GLUCOSE TRANSPORT.

Authors:  J VANSTEVENINCK; R I WEED; A ROTHSTEIN
Journal:  J Gen Physiol       Date:  1965-03       Impact factor: 4.086
  8 in total
  2 in total

1.  Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility.

Authors:  Rishi B Parikh; Moez Bali; Myles H Akabas
Journal:  J Biol Chem       Date:  2011-03-01       Impact factor: 5.157

2.  Mercury compounds: lipophilicity and toxic effects on isolated myocardial tissue.

Authors:  S Halbach
Journal:  Arch Toxicol       Date:  1990       Impact factor: 5.153
  2 in total

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