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Literature DB >> 4026262

Inducible phenotypic multidrug resistance in the fungus Mucor racemosus.

Abstract

The dimorphic fungus Mucor racemosus exhibited a single-step, inducible resistance to cycloheximide, trichodermin, and amphotericin B. Cells adapted to inhibitory levels of the antibiotics after 12 to 40 h. The adaptation involved all the cells in the population and was not the result of the selection of resistant mutants. Adaptation to one drug provided cross resistance to other, dissimilar drugs. Resistance was lost within several generations of growth in the absence of the inhibitors.

Entities: Chemical Species

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Year: 1985 PMID： 4026262 PMCID： PMC180181 DOI： 10.1128/AAC.27.6.892

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

17 in total

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Authors: I F Salkin
Journal: Can J Microbiol Date: 1975-09 Impact factor: 2.419

2. THE EFFECT OF 5-FLUORODEOXYURIDINE ON GENETIC REPLICATION AND MITOTIC CROSSING OVER IN SYNCHRONIZED CULTURES OF USTILAGO MAYDIS.

Authors: R E ESPOSITO; R HOLLIDAY
Journal: Genetics Date: 1964-11 Impact factor: 4.562

3. Antimicrobial agents. XIX. Detoxication mechanism of some strains of Candida albicans.

Authors: A Capek; L Pavlíková; A Simek; L Brůna; V Janata; Z Budĕsínský
Journal: Folia Microbiol (Praha) Date: 1973 Impact factor: 2.099

4. Development of strains of Cryptococcus neoformans resistant to nystatin, amphotericin B, trichomycin and polymyxin B.

Authors: J Bodenhoff
Journal: Acta Pathol Microbiol Scand Date: 1968

5. Transient inhibition by cycloheximide of protein synthesis in cultured plant cell suspensions: a dose response paradox.

Authors: M E Davies; C P Exworth
Journal: Biochem Biophys Res Commun Date: 1973-02-20 Impact factor: 3.575

6. Antimicrobial agents. 28. Inducible resistance in species of the genus Candida.

Authors: A Capek; A Simek; J Kejda
Journal: Folia Microbiol (Praha) Date: 1973 Impact factor: 2.099

7. Quantitative evaluation of the antifungal properties of cycloheximide.

Authors: I F Salkin; N Hurd
Journal: Antimicrob Agents Chemother Date: 1972-03 Impact factor: 5.191

8. Antimicrobial agents. VI. Antimycotic activity and problems of resistance.

Authors: A Capek; A Simek; J Leiner; J Weichet
Journal: Folia Microbiol (Praha) Date: 1970 Impact factor: 2.099

9. The effect of the herbicide 2,4,5 trichlorophenoxy acetic acid (245T) on the growth and metabolism of Tetrahymena pyriformis.

Authors: G B Silberstein; A B Hooper
Journal: J Cell Physiol Date: 1975-04 Impact factor: 6.384

10. On the mechanism of adaptation to protein synthesis inhibitors by Tetrahymena. Facilitation, cross adaptation, and resensitization.

Authors: C T Roberts; E Orias
Journal: J Cell Biol Date: 1974-09 Impact factor: 10.539

5 in total

1. Cycloheximide efflux in antibiotic-adapted cells of the fungus Mucor racemosus.

Authors: G Shearer; P S Sypherd
Journal: Antimicrob Agents Chemother Date: 1988-03 Impact factor: 5.191

Review 2. Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon.

Authors: M N Alekshun; S B Levy
Journal: Antimicrob Agents Chemother Date: 1997-10 Impact factor: 5.191

Review 3. Systemic zygomycosis.

Authors: E W Benbow; R W Stoddart
Journal: Postgrad Med J Date: 1986-11 Impact factor: 2.401

4. Trichodermin esterase activity and trichodermin resistance in Mucor racemosus.

Authors: W A Fonzi; P S Sypherd
Journal: Antimicrob Agents Chemother Date: 1986-04 Impact factor: 5.191

5. Antifungal-resistant Mucorales in different indoor environments.

Authors: Liliana Aranha Caetano; Tiago Faria; Jan Springer; Juergen Loeffler; Carla Viegas
Journal: Mycology Date: 2018-11-26

5 in total