Literature DB >> 4026020

Comparative pharmacokinetics of febantel and its metabolites in sheep and cattle.

P Delatour, M P Tiberghien, F Garnier, E Benoît.   

Abstract

The pharmacokinetics of febantel and its main metabolites were studied in cattle and sheep. Seven ewes and 4 heifers were given febantel orally in a single dose of 7.5 mg/kg, 25 mg/kg, or 45 mg/kg of body weight. Plasma concentrations vs time of febantel and individual metabolites were determined by high-performance liquid chromatography analysis. Intestinal absorption of febantel was faster and biotransformations were more active in sheep than in cattle.

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Year:  1985        PMID: 4026020

Source DB:  PubMed          Journal:  Am J Vet Res        ISSN: 0002-9645            Impact factor:   1.156


  2 in total

1.  [Esophageal closure and the efficacy of febantel against Muellerius capillaris in goats].

Authors:  C Chartier; A Kulo; P Delatour; J Cabaret
Journal:  Can Vet J       Date:  1995-11       Impact factor: 1.008

2.  The pharmacokinetics of fenbendazole and oxfendazole in cattle.

Authors:  A J Ngomuo; S E Marriner; J A Bogan
Journal:  Vet Res Commun       Date:  1984-08       Impact factor: 2.459

  2 in total

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