Literature DB >> 402566

[The effect of antacids on stress-induced lesions of the gastric mucosa in the piglet (author's transl)].

J G Doertenbach, C Hottenrott, M Büsing, L Gerstenbergk, W Ruf.   

Abstract

After administration of antacids, gastric stress lesions due to hemorrhagic shock appear in the pig stomach quicker and more markedly than in animals which have been similarly treated with an indifferent substance or not at all. However, once treated, the administration of antacids seems to favor the healing of mucosal lesions after the end of the stress. At the same time it was observed that after administration of antacids in hemorrhagic shock, the serum gastrin level rises and does not remain constant, as in the control group. An attempt is made to explain the favorable effect of antacids on the genesis of hemorrhagic stress lesions in the pig's stomach through this observation.

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Year:  1977        PMID: 402566

Source DB:  PubMed          Journal:  MMW Munch Med Wochenschr        ISSN: 0341-3098


  1 in total

1.  [Pancreatic juice and stress ulcers of the rat (author's transl)].

Authors:  V Schumpelick; D Grossner; M Doehn
Journal:  Langenbecks Arch Chir       Date:  1977-12-14
  1 in total

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