Literature DB >> 4024136

Tetrodotoxin derivatives in puffer fish.

M Nakamura, T Yasumoto.   

Abstract

Analysis of puffer fish tissue extracts by a fluorometric tetrodotoxin analyzer revealed the presence of three tetrodotoxin derivatives besides tetrodotoxin. The derivatives were isolated and identified as tetrodonic acid, 4-epitetrodotoxin and anhydrotetrodotoxin on the basis of mass spectral and 1H NMR measurements. The lethal potencies of 4-epitetrodotoxin and anhydrotetrodotoxin to mice by i.p. injection were 710 and 92 mouse units/mg, respectively.

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Year:  1985        PMID： 4024136     DOI： 10.1016/0041-0101(85)90149-7

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  18 in total

1.  Effect of insulin on Blattela germanica Linnacus.

Authors:  E Abolghasemi; Kazem S H Moosa; M Abolhasani; M Davoudi
Journal:  Asian Pac J Trop Biomed       Date:  2011-08

Review 2.  Behavioral and chemical ecology of marine organisms with respect to tetrodotoxin.

Authors:  Becky L Williams
Journal:  Mar Drugs       Date:  2010-02-26       Impact factor: 5.118

3.  LC/MS analysis of tetrodotoxin and its deoxy analogs in the marine puffer fish Fugu niphobles from the southern coast of Korea, and in the brackishwater puffer fishes Tetraodon nigroviridis and Tetraodon biocellatus from Southeast Asia.

Authors:  Jun-Ho Jang; Jong-Soo Lee; Mari Yotsu-Yamashita
Journal:  Mar Drugs       Date:  2010-03-31       Impact factor: 5.118

4.  Resurgent-like currents in mouse vas deferens myocytes are mediated by NaV1.6 voltage-gated sodium channels.

Authors:  Noriyoshi Teramoto; Hai-Lei Zhu; Mari Yotsu-Yamashita; Tetsuichiro Inai; Thomas C Cunnane
Journal:  Pflugers Arch       Date:  2012-09-18       Impact factor: 3.657

5.  Effects of 4,9-anhydrotetrodotoxin on voltage-gated Na+ channels of mouse vas deferens myocytes and recombinant NaV1.6 channels.

Authors:  Kohei Takahara; Tadashi Yamamoto; Keiichiro Uchida; Hai-Lei Zhu; Atsushi Shibata; Tetsuichiro Inai; Mitsuru Noguchi; Mari Yotsu-Yamashita; Noriyoshi Teramoto
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2018-02-16       Impact factor: 3.000

6.  Interactions of the C-11 hydroxyl of tetrodotoxin with the sodium channel outer vestibule.

Authors:  Gaurav Choudhary; Mari Yotsu-Yamashita; Lisa Shang; Takeshi Yasumoto; Samuel C Dudley
Journal:  Biophys J       Date:  2003-01       Impact factor: 4.033

7.  Isolation and structural determination of the first 8-epi-type tetrodotoxin analogs from the newt, Cynops ensicauda popei, and comparison of tetrodotoxin analogs profiles of this newt and the puffer fish, Fugu poecilonotus.

Authors:  Yuta Kudo; Takeshi Yasumoto; Keiichi Konoki; Yuko Cho; Mari Yotsu-Yamashita
Journal:  Mar Drugs       Date:  2012-03-22       Impact factor: 6.085

Review 8.  Selective blocking effects of 4,9-anhydrotetrodotoxin, purified from a crude mixture of tetrodotoxin analogues, on NaV1.6 channels and its chemical aspects.

Authors:  Noriyoshi Teramoto; Mari Yotsu-Yamashita
Journal:  Mar Drugs       Date:  2015-02-12       Impact factor: 5.118

9.  First identification of 5,11-dideoxytetrodotoxin in marine animals, and characterization of major fragment ions of tetrodotoxin and its analogs by high resolution ESI-MS/MS.

Authors:  Mari Yotsu-Yamashita; Yuka Abe; Yuta Kudo; Raphael Ritson-Williams; Valerie J Paul; Keiichi Konoki; Yuko Cho; Masaatsu Adachi; Takuya Imazu; Toshio Nishikawa; Minoru Isobe
Journal:  Mar Drugs       Date:  2013-08-06       Impact factor: 5.118

10.  Tetrodotoxin and Its Analogues in the Pufferfish Arothron hispidus and A. nigropunctatus from the Solomon Islands: A Comparison of Their Toxin Profiles with the Same Species from Okinawa, Japan.

Authors:  Clyde Gorapava Puilingi; Yuta Kudo; Yuko Cho; Keiichi Konoki; Mari Yotsu-Yamashita
Journal:  Toxins (Basel)       Date:  2015-08-26       Impact factor: 4.546
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