Literature DB >> 4022004

Effect of prolactin and glucocorticoids on P-enolpyruvate carboxykinase activity in liver and mammary gland from diabetic and lactating rats.

M F Lobato, M Careche, M Ros, F J Moreno, J P García-Ruíz.   

Abstract

The administration of 2 bromo-alpha-ergocryptine, to reduce serum prolactin decreased the activity of cytosolic P-enolpyruvate carboxykinase (GTP) (EC 4.1.1.32) about 50% in both liver and mammary gland of lactating animals. Adrenalectomy had similar effects to those of bromo-alpha-ergocryptine. In contrast, there was a 50% increase in enzyme activity in the mammary gland of diabetic, lactating rats and a 10-fold increase in liver as compared with normal rats. P-enolpyruvate carboxykinase activity in mammary gland as liver is coordinately regulated by prolactin, glucocorticoids and insulin.

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Year:  1985        PMID： 4022004     DOI： 10.1007/bf00220981

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  40 in total

1.  Uptake and metabolism of plasma glutamine by the small intestine.

Authors:  H G Windmueller; A E Spaeth
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2.  Adenosine 3':5'-monophosphate and hormone interrelationships in the mammary gland of the rat during pregnancy and lactation.

Authors:  M Sapag-Hagar; A L Greenbaum
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3.  Dynamics of insulin release by perfused rat pancreases: effects of hypophysectomy, growth hormone, adrenocorticotropic hormone, and hydrocortisone.

Authors:  D L Curry; L L Bennett
Journal:  Endocrinology       Date:  1973-09       Impact factor: 4.736

4.  The formation of ammonia from glutamine and glutamate by mitochondria from rat liver and kidney.

Authors:  F J Hird; M A Marginson
Journal:  Arch Biochem Biophys       Date:  1968-09-20       Impact factor: 4.013

5.  Rat mammary acetyl coenzyme A carboxylase. I. Isolation and characterization.

Authors:  A L Miller; H R Levy
Journal:  J Biol Chem       Date:  1969-05-10       Impact factor: 5.157

6.  Rate-limiting steps in metabolic pathways.

Authors:  R Rognstad
Journal:  J Biol Chem       Date:  1979-03-25       Impact factor: 5.157

7.  Messenger RNA for renal phosphoenolpyruvate carboxykinase (GTP). Its translation in a heterologous cell-free system and its regulation by glucocorticoids and by changes in acid-base balance.

Authors:  P B Iynedjian; R W Hanson
Journal:  J Biol Chem       Date:  1977-12-10       Impact factor: 5.157

8.  3,5,3'-Triiodothyronine-induced synthesis of rat liver phosphoenolpyruvate carboxykinase.

Authors:  M J Müller; A Thomsen; W Sibrowski; H J Seitz
Journal:  Endocrinology       Date:  1982-11       Impact factor: 4.736

9.  Comparison of glucose metabolism in the lactating mammary gland of the rat in vivo and in vitro. Effects of starvation, prolactin or insulin deficiency.

Authors:  A M Robinson; D H Williamson
Journal:  Biochem J       Date:  1977-04-15       Impact factor: 3.857

10.  Presence of cytosolic phosphoenolpyruvate carboxykinase activity in rat mammary gland.

Authors:  J P García-Ruíz; M F Lobato; M Ros; F J Moreno
Journal:  Enzyme       Date:  1983
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  2 in total

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Authors:  R S Eisenstein; J M Rosen
Journal:  Mol Cell Biol       Date:  1988-08       Impact factor: 4.272

2.  Function of phosphoenolpyruvate carboxykinase in mammary gland epithelial cells.

Authors:  Chang-Wen Hsieh; Charles Huang; Ilya Bederman; Jianqi Yang; Michelle Beidelschies; Maria Hatzoglou; Michelle Puchowicz; Colleen M Croniger
Journal:  J Lipid Res       Date:  2011-04-19       Impact factor: 5.922
  2 in total

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